Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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- The metabolic pathway responsible for clearing lactic acid from our bodies is called the Cori Cycle. It occurs in the liver, and converts lactic acid back into pyruvic acid, and then into glucose. The glucose can then be used for energy metabolism again. However, the Cori Cycle requires a net input of 4 ATP to operate. Based on this information how can you describe the Cori Cycle? [Select any/all that apply.] Cori Cycle is exergonic. Cori Cycle is anabolc. Cori Cycle is catabolic. Cori Cycle is endergonic.arrow_forwardExplain in detail of the process of cellular respiration, including all the stages of cellular respiration (glycolysis, pyruvate oxidation, citric acid cycle, and oxidative phosphorylation) and explain the substrate and product of each pathway. And make a table of the products formed at the end of glycolysis, pyruvate oxidation, citric acid cycle, and oxidative phosphorylation (ATPs, NADHs, water, and carbon dioxide). Then discuss about oxidation-reduction of various molecules that are a part of these pathways.arrow_forwardGive all the reactions that will produce ATP either by substrate-level phosphorylation (SLP) or by oxidative phosphorylation (OP). If the given require a shuttle system, please indicate both MA shuttle and GP shuttle and give the ATP produced. Given: fructose 6-phosphate to 2pyruvatearrow_forward
- Using the following glycolisis diagram, a. name all the steps in citric acid cycle, what are the intermediates. refer to the diagram given. b. Is glycolysis endothermic or exothermic.arrow_forwardWhat if the phosphate group for the glycolysis reaction with enzyme glyceraldehyde 3-phosphate dehydrogenase was from ATP instead of Pi? What would the complete, balanced, net rxn of glycoslysisequation be and how does this impact the overall glycolysis rxn?arrow_forwardShow sequentially, the total ATP Yield and the net ATP Yield in the complete oxidation of Glucose (from Glycolysis to Oxidative Phosphorylation) in the Muscle and Heart Tissues of a man. Indicate the differences in the ATP yield in both tissues.arrow_forward
- Calculate the energy(Kcal.) produced from full oxidation of (3) mole of glucose (glucose --> CO2+ H2O), Compare the energy yield with that produced from oxidation of (1) mole .of stearic acid (C18)arrow_forwardWhat is meant by reciprocal regulation ? Name one compound that reciprocally regulates glycolysis and gluconeogenesis pathways . Which enzymes are regulated by this compound? What reactions are catalyzed by these enzymes (structures not required) ?arrow_forwardWhen ATP and xylose are added to hexokinase, the enzyme produces a small amount of xylose-5-phosphate along with a large amount of ADP. How does this observation support the induced fit model?arrow_forward
- Free energy changes under intracellular conditions differ markedly from those determined under standard conditions. ΔG°′ = -32.2 kJ/mol for ATP hydrolysis to ADP and Pi. Calculate ΔG for ATP hydrolysis in a cell at 37 °C that contains [ATP] = 3 mM, [ADP] = 1 mM, and 3Pi4 = 1 mM.arrow_forwardCalculate the number of ATPATP generated from one saturated 1212‑carbon fatty acid. Assume that each NADHNADH molecule generates 2.5 ATP2.5 ATP and that each FADH2FADH2 molecule generates 1.5 ATP1.5 ATP .arrow_forwardThe AG of the reaction C6H12O6 + 60₂ --> 6CO₂ + 6H₂O is -686 kcal/mol glucose oxidized. The AG of the reaction ADP + P₁ --> ATP + H₂O is + 7.3 kcal/mol ATP synthesized. The oxidation of glucose can be coupled to the synthesis of ATP. If the coupling is 50% efficient, how many molecules of ATP can be synthesized per molecule of glucose oxidized? Round your answer to the nearest whole number.arrow_forward
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