What is genomic instability? Give some ways in which genomic instability may arise.

Q: What is central dogma of molecular genetics? How does it work ?

A: The Central Dogma was first proposed in 1958 by Francis Crick. He was also the discoverer of the…

Q: Describe how P elements are used to producetransgenic Drosophila.

A: Genetics is a branch of science that deals in the study of genes, heredity, and genetic variation of…

Q: 1. a)What would happen if the aminoacyl tRNA synthetase responsible for charging alanine tRNAs also…

A: The polymerization of amino acids according to the codons on mRNA to form proteins is known as…

Q: A Drosophila embryo dies during early embryogenesis due to arecessive allele of a maternal effect…

A: Phenotypes and genotypes represents the traits that gets passed on from the parents to the progeny.…

Q: What is a transversion mutation?

A: Mutations are the alterations or the changes that occur in the DNA. Mutations are variations in…

Q: What is a mutation? How does a mutation lead to an altered phenotype? Describe two specific types of…

A: The cell is the basic structural and functional unit of the body. A cell is composed of various cell…

Q: What mutations are possible in gene ZFPM2?

A: ZFPM 2 is a multi zinc finger protein. It helps in transcription regulation of certain genes by…

Q: What is a telomere problem and how is telomerase useful in this context?

A: Telomere is the sequence of repetitive nucleotides present at the ends of the chromosomes. Telomeres…

Q: Explain Deletion-insertion polymorphisms (DIPs)?

A: DIPs or Deletion-Insertion polymorphisms is defined as a large number of consistent genetic variants…

Q: Fragile X syndrome What are the symptoms or characteristics of this disorder or trait?  What is…

A: Fragile X syndrome   Fragile X syndrome (FXS) is a disorder which causes mainly mental and…

Q: Define deletion-insertion polymorphisms (DIPs)

A: Insertion is a mutation in which one or more nucleotide base pairs are added into a DNA sequence.…

Q: How were the specific sequences of triplet codes determined experimentally?

A: The DNA genetic code comprises a set of rules and instructions to obtain proteins and molecules…

Q: Among different species, describe three distinct mechanisms foraccomplishing dosage compensation.

A: Dosage compensation is a mechanism by which organisms equalize the gene expression between different…

Q: What are the possible genotypes of the PTC locus?

A: * genotype means collection of genes that  refers to two alleles of a particular gene and genotype…

Q: What Genetic Conditions Are Candidates for Treatment by GeneTherapy?

A: The Genetic Conditions Are Candidates for Treatment by Gene Therapy are: • These cells can be…

Q: Are there nucleotide substitutions that will not be detected by electrophoretic studies of a gene’s…

A: SPONTANEOUS MUTATION:-  1) SUBSTITUTION:-  Substitution of base pairs is the most common mutation,…

Q: How common is dup15q?

A: Dup15q:- Is characterized by having an extra copy of a portion  of chromosome 15[partial trisomy] in…

Q: How to identify all the somatic mutationswithin tumors ?

A: A somatic mutation is a modification within the desoxyribonucleic acid sequence of a somatic cell of…

Q: How can telomerase-related aging be addressed therapeutically?

A: Introduction DNA is packed inside the cell in the form of chromosomes and chromatin. The…

Q: Why are maternal effect genes so difficult to identify via mutant analysis?

A: Introduction :- In an offspring , the genes are contributed by both of the parents but the mother…

Q: What are the most well-studied chromatin remodelers?

A: Deoxyribonucleic acid or DNA is a double helix nucleic acid structure that carries the genetic…

Q: How is telomerases related to ageing? How Can telomerase- related ageing be addressed…

A: Humans lose physiological and psychological function as they age, which is a normal process. The…

Q: What are paralogous and orthologous genes? What are some of the explanations for the finding that…

A: Thus, a gene is a fundamental unit of inheritance, carrying coded information associated with a…

Q: During construction of a knockout mouse, a targeting vector is introduced into mouse embryonic…

A: Gene targeting is the technique of changing a specific sequence or gene at its location in a genome…

Q: Describe the difference in the effects of a mutation in a gap gene versus one in a pair-rule gene.

A: The genes consist of hereditary information in the deoxyribonucleic acid (DNA) sequences and is…

Q: describe Deletion-insertion polymorphisms (DIPs)

A: Polymorphism: Many forms of a allele is termed as polymorphism. The polymorphism leads to the…

Q: How is a genome-wide association study carried out?

A: Deoxyribonucleic acid (DNA) is a genetic material of most organisms. DNA contains the instructions…

Q: What community-based genetic screening programs? What is the intent of such screening programs? Why…

A: A community or population-based genetic screening programme is any type of test performed for the…

Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.