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Q: How does a dideoxynucleotide differ from a deoxynucleotide?
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What is 7-methylguanosine (m7G) cap ?
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- What are Okazaki fragments? Why are they formed?Draw and label the following RNA tetranucleotide: 5’phosphoryl-A-2’O-methyl-C-U-G-3’-phosphateMolnupiravir causes widespread mutations as SARS-CoV-2 replicates its genome because in an RNA double helix molnupiravir can base pair with more than one base. Shown below are the structures the RNA bases. With which two bases does molnupiravir pair? H N-H Adenine NH-N Uracil H H-N N-HN N-H Guanine H Cytosine A. The "imino" form pairs with A; the "amino" form pairs with G. B. The "imino" form pairs with G; the "amino" form pairs with A. C. The "imino" form pairs with U; the "amino" form pairs with C. D. The "imino" form pairs with C, the "amino" form pairs with U.
- What is the beta-pleated sheet?Given the following Wild Type and Mutated DNA sequences: 1.) Identify where the base pair change occurs (what letters changed?) 2.) For BOTH sequences, write the mRNA strands, define the codon regions (with spaces), and amino acid sequences. 3.) Describe what kind of mutation has occurred (missense, nonsense, or silent), and what effect this may have on the protein. Wild Type DNA Sequence: 3' - CCTCGTTATGTG - 5' Mutated DNA Sequence: 3' - CCTCGTTATTTG - 5'Why is the α-helix so prevalent?
- How is a dideoxynucleotide different from a deoxynucleotide?What interactions stabilize the formation of a B-sheet from B-strands? a) Salt bridges from charged R groups b) Hydrogen bonds between the backbone c) Hydrogen bonds between R groups d) Burial of hydrophobic residues e) None of the above interactions stabilize the formation of a a B-sheet hint: beta-sheets are what level of structure and how is that level stabilizedTRUE OR FALSE a) Primary amines and keto groups of the nitrogen bases are involved in base-pairing in double stranded DNA. b) The unique stem-loop structures of the transfer RNA helps the RNA perform its function of joining ribosomal proteins to form the sites for protein synthesis.