What glucose transport protein is insulin independent and expressed on the beta cells of the pancreas? O GLUT 1 O GLUT 2 O GLUT 3 O GLUT 4

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
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### Glucose Transport Proteins in Beta Cells of the Pancreas

#### Question: 
What glucose transport protein is insulin independent and expressed on the beta cells of the pancreas?

#### Answer Options:
- ☐ GLUT 1
- ☐ GLUT 2
- ☐ GLUT 3
- ☐ GLUT 4

---

### Detailed Explanation:

**GLUT Proteins:** 
Glucose transport proteins (GLUTs) are a family of membrane proteins that facilitate the transport of glucose across the plasma membrane. They are essential for the uptake of glucose by cells from the bloodstream.

**Insulin-independent Transport:**
While some GLUT proteins require insulin to function effectively, others do not, meaning they can uptake glucose without the presence of insulin. This is particularly important in tissues where glucose uptake must be constant and not influenced by insulin levels.

**Beta Cells of the Pancreas:**
Beta cells are located in the pancreas and are responsible for the production and secretion of insulin. The proper function of these cells is crucial for maintaining blood glucose levels.

Understanding which GLUT protein is expressed on the beta cells of the pancreas and operates independently of insulin is key for grasping how glucose regulation occurs in the body under varying conditions. This knowledge is also important for understanding various metabolic and diabetic conditions, where glucose transport can be significantly affected.
Transcribed Image Text:### Glucose Transport Proteins in Beta Cells of the Pancreas #### Question: What glucose transport protein is insulin independent and expressed on the beta cells of the pancreas? #### Answer Options: - ☐ GLUT 1 - ☐ GLUT 2 - ☐ GLUT 3 - ☐ GLUT 4 --- ### Detailed Explanation: **GLUT Proteins:** Glucose transport proteins (GLUTs) are a family of membrane proteins that facilitate the transport of glucose across the plasma membrane. They are essential for the uptake of glucose by cells from the bloodstream. **Insulin-independent Transport:** While some GLUT proteins require insulin to function effectively, others do not, meaning they can uptake glucose without the presence of insulin. This is particularly important in tissues where glucose uptake must be constant and not influenced by insulin levels. **Beta Cells of the Pancreas:** Beta cells are located in the pancreas and are responsible for the production and secretion of insulin. The proper function of these cells is crucial for maintaining blood glucose levels. Understanding which GLUT protein is expressed on the beta cells of the pancreas and operates independently of insulin is key for grasping how glucose regulation occurs in the body under varying conditions. This knowledge is also important for understanding various metabolic and diabetic conditions, where glucose transport can be significantly affected.
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