What are “forcefields” and how are they used in predicting how a protein sequence will fold?

Q: How do you identify the N vs C terminals?  For the first part of the question, do you then list the…

A: Amino acids are the monomers of a polypeptide or protein. Amino acids contain an amino (-NH2) group…

Q: What physical parameters of a protein control its migration on electrophoresis?

A: Electrophoresis is a laboratory technique used to separate DNA, RNA, or protein molecules in the…

Q: Write the Structure Activity Relationship ( SAR)  of Captopril ?

A: Captopril is an antihypertensive drug and is used for the treatment of renovascular hypertension. It…

Q: What is a magnetosome?

A: The cellular magnetic dipole moments are often large enough, so their interaction with Earth’s…

Q: To construct an “interactome” like the one shown in Figure 9-21, scientists identify all of the…

A: In molecular biology, interactomes is defined as the whole group for molecular interactions in a…

Q: What is the importance of 'protein-folding chaperones'

A: When the DNA transcripts to an mRNA, the mRNA is translated to the protein molecule which is encoded…

Q: How do nucleotide codon sequences determine the primary amino acid sequence of a nascent protein?

A: Codon is found in mRNA. It consists of three ribonucleotides. It encodes a particular amino acid.

Q: What are the three major types of RNA molecules? How is eachrelated to the concept of information…

A: Ribonucleic acid is a polymeric molecule essential in various biological roles in coding, decoding,…

Q: What are the A site and the P site? How are their roles in protein synthesis similar? How do they…

A: The protein is a principle component of all the cell. It is an organic compound that is made of one…

Q: Using sickle-cell anemia as a basis, describe what is meant by a genetic or inherited molecular…

A: A disease is an abnormal condition of the body or body that does not work properly and causes a…

Q: How many human proteins are in the range of 250,000 to 900,000 Daltons?

A: The human body is thought to have over a million different types of protein, and even a single-cell…

Q: In kilodaltons (KDa), what is the predicted molecular mass of the protein encoded by this gene…

A: Molecular weight of the protein can be calculated by adding the molecular weight of the individual…

Q: What is the most consistently (i.e. found in every case) energetically unfavorable aspect of protein…

A: People have developed molecular dynamics simulations of the basic atomic forces that determine a…

Q: What are different kind of forces present in primary , secondary and Tertiary structure of protein .…

A: The basic structural and functional units of proteins are amino acids. They are the monomeric units…

Q: How do scientists make the migration rates of proteins reflect their molecular weights (sizes) and…

A: In electrophoresis migration is dependent on the size. Smaller fragments migrate faster than larger…

Q: What are the possible phosphorylation sites in a target protein?

A: Protein phosphorylation It is defined as the process of reversible post translational modification…

Q: Define the following terms:a. protein motifb. conjugated proteinc. dyneind. zwitterione.…

A: Introduction: Proteins are major biomolecules that consist of long chains of amino acids. The…

Q: If DNA concentration is 2 grams, what would be the molar concentration of human DNA in a human cell?

A: Introduction: DNA, or deoxyribonucleic acid, is the genetic substance found in humans and virtually…

Q: What is Centrioles in biology?

A: Eukaryotic cells are contain a organelles and a nucleus and are enclosed by a plasma membrane.…

Q: Experimentally, what are some ways to investigate a protein's function/s or loss of it?

A: Proteins are composed of amino acids, which are bound together by peptide linkage. Amino acids…

Q: What are known as protein domains ? How do they work ?

A: Proteins are enormous biomolecules or macromolecules that are contained at least one long chain of…

Q: What is denaturation? Give examples. What are the factors that affects the proteir synthesis?

A: Proteins are defined as an unbranched polymers which are made up of 22 amino acids. They are usually…

Q: What is denaturation? Give examples. What are the factors that affects the protein synthesis?

A: Protein is macromolecule that is vital for maintaining muscle mass.

Q: What is the concept of FoldIt protein folding game, and how is it used to elucidate and visualize…

A: The Department of Biochemistry and the Center for Game Science at the University of Washington…

Q: How does Foldit Protein Folding Game use puzzles like Design, De Novo, Revisiting, help in…

A: The Department of Biochemistry and the Center for Game Science at the University of Washington…

Q: What are the four different point mutations? How can genetic mutation (genotype) alter protein…

A: Point mutations are chromosome rearrangements. They are usually the consequence of errors made…

Q: What are the steps required to attach ubiquitin to a target protein?

A: Proteins contain amino acid chains. After the synthesis of proteins, they are folded with the help…

Q: As we focused on the translation of mRNA into proteins as well as on protein structure and function.…

A: One gene one enzyme hypothesis, proposed by Beadle and Tatum, says that each enzyme produces a…

Q: What is Initiator element (Inr) ?

A: Nucleic acid is one of the major macromolecules that are present in living organisms. It contains…

Q: What is the major driving force that works in favor of tertiary protein structure formation (protein…

A: Proteins are the complex macro molecules that show four levels of structural organisation. They are…

Q: Cystic fibrosis (CF) is an inherited disorder caused by different types of mutations, many of which…

A: CF is caused by a mutation in a gene called the cystic fibrosis transmembrane conductance regulator…

Q: What is isosterism and bioisostreism? How does this concept help in biotransformation of different…

A: In biology, drug designing is a major aspect. Drug specificity and effectivity are determined by…

Q: Erk and P-Erk live in two different locations within the cell even though they are just two…

A: * Mitogen activated protein kinase also called as  MAPK and  p42MAPK, and ERK2 * It is an enzyme…

Q: What are molecular chaperones or chaperonins ?

A: The protein is synthesized and attains full conformation for the functioning of the matured protein.…

Q: What is the role of enzyme “Ligase” in genetic Engineering?

A: Recombinant DNA technology is not a simple process. It aims at isolating desired DNA sequences from…