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Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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What are 3 functions of the classical complement pathway
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- 1arrow_forwardSome individuals with immunodeficiency have mutations in the digesting enzymes of their macrophages. What impact might this have on their immune systems? Question 8 options: The adaptive immune response may no longer be activated. Macrophage will no longer recognize the PAMPs with their TLRs. Macrophages will not release cytokines upon tissue damage. MHC receptors will present antigens on the surface of the macrophages.arrow_forwardThree effects of complement activation: (1) inflammation (2) opsonization (3) cytolysis of pathogens. Describe the three effects in at least one complete sentence for each. You should clearly explain *how* complement activation results in the three different effects.arrow_forward
- Which of the following is false about complement? O Complement kills pathogens by inducing cell lysis Complement are a series of proteins that circulate through the blood Complement is produced by the kidney Complement enhances phagocytosis. ооооarrow_forwardComplement could be one example of a ?????, one of the three types of defenses employed by the innate immune system.arrow_forwardDescribe the steps in the classical complement pathway making sure to include the three ways the pathway aids in destroying pathogensarrow_forward
- 5. Results from complement activation and the functions of key components. Mechanisms. (A). Lysis - breaking holes through membrane (B). Induce inflammation (anaphylatoxin) (C). Opsonization Opsonins (D). Augment adaptive response (E). Clearance of soluble immune complexes (Ag/Ab) and apoptotic cells.arrow_forwardJohnny has just been infected and needs your help in letting him know how his body is fighting the infection. To do so, describe how the innate and adaptive immune systems work together. You should address the following: 1. define adaptive and innate immunity; 2. Describe the role of natural killer cells (how do they work); 3. what are antigen presenting cells and what is their function, what are MHCs?; 4. describe the role of the complement system; 5. what is the role of interferons?; 6. How do helper T cells, cytotoxic T cells and B lymphocytes work make sure you address adaptive immunity memory?; 7. Define HIV, which cells do they attack and why do some individuals develop persistent lymphadenopathy (swollen or enlarged lymph nodes)?arrow_forward
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