What acid chloride would be needed to prepare the following ketone from benzene using a Friedel-Crafts acylation? Click the "draw structure" button to launch the drawing utility.
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- Synthesize Chloramphenicol from Toluene or Benzaldehyde. Draw and explain step by step please.(p.s: if you can, can you write what the reagents does?) (Drug Chemistry)a) Write out the first 3 steps only(to the tetrahedral intermediate shown) in the 6-step arrow pushing mechanism showing how ethyl propanoate is hydrolyzed in acid to form propanoic acidand ethanol. b) NaOH/H2O also serveto hydrolyze an ester; briefly explain why NaOH/H2Ois generally preferable.Give a clear handwritten answer with explanation..provide the IUPAC name of given bleow structure
- Menthone and menthol are both isolated from mint. Explain why mentholis a solid at room temperature but menthone is a liquid. (see attached)1) How will you describe whether any compound has been oxidized or reduced? Support the answer with suitable examples. 2)Why carboxylic acid with a carbonyl group at 3rd position can be decarboxylated? 3) Explain why electrophilic aromatic substitution in Pyrrole takes place at C-2 positions whereas, in Pyridine it takes place at C-3 position? 4) List the following esters in order of decreasing reactivities towards hydrolysis with reason: Methyl benzoate, p-cyano methyl benzoate and p-hydroxy methyl benzoate 5)LDA is the base of choice for carbonyl compound to completely convert into enolate. Why?a) Put these three common types of carbonyl compound in order of decreasing reactivity ester amide acid chloride b) For the least reactive, show the interconversion to its other resonance form: How does this electron delocalisation make it stable? c) For the most reactive, draw the mechanism of its undergoing hydrolysis (reaction with H2O): Why makes this type of carbonyl so reactive to nucleophiles?
- please help with this question. thank you. n-acetylazoles go through hydrolysis more than regular amides. propose a reason for the reactivity of n-acetylazoles toward nucleophilic substitution.What is difference between the acetoacetic and malonic ester syntheses? Provide an example of each, including all intermediates..Draw the principal organic product for the reaction of 2-bromobutane with magnesium in diethyl ether, followed with benzaldehyde in diethyl ether, and then followed by dilute acid...
- Based on the following groups Acid chloride, Amide, Ester a) Select the most reactive group towards nucleophilic acyl substitution reaction. b) Describe the reasons in question (a). c) Identify the group(s) that can been synthesized from acid chloride.What experimental means may be used to drive an esterification towards completion?Answer the following organic react