"We would have no idea today of the importance of insulin as a regulatory hormone if its absence were not associated with the human disease diabetes. It is the dramatic consequences of its absence that focused early efforts on the identification of insulin and the study of its normal role in physiology."

"We would have no idea today of the importance of insulin as a regulatory hormone if its absence were not associated with the human disease diabetes. It is the dramatic consequences of its absence that focused early efforts on the identification of insulin and the study of its normal role in physiology."

Essentials of Pharmacology for Health Professions

7th Edition

ISBN:9781305441620

Author:WOODROW

Publisher:WOODROW

Chapter23: Endocrine System Drugs

Section: Chapter Questions

Problem 15CRQ

See similar textbooks

Similar questions

Discuss the following statement: “We wouldhave no idea today of the importance of insulin as a reg-ulatory hormone if its absence were not associated withthe human disease diabetes. It is the dramatic conse-quences of its absence that focused early efforts on theidentification of insulin and the study of its normal role inphysiology.”
Why do you suppose individuals with diabetes must receive insulin subcutaneously by injection rather than orally?
You work for a pharmaceutical company where you are assigned the task of creating new drug therapies to treat thyroid disorders such as hyperthyroidism (high levels of T3 and T4) and hypothyroidism (low levels of T3 and T4). Your team has designed a few drugs, and your job is to identify which drug(s) would be successful in treating thyroid disorders based on your knowledge of thyroid hormone synthesis. Below is the list of drugs your team designed (all of these are hypothetical drugs). Peroxidine: A drug that inhibits thyroid peroxidase from functioning Cimigine: A drug that inhibits potassium/iodine cotransporter Iodimine: A drug that inhibits iodinase from functioning Aldosine: A drug that inhibits production of angiotensinogen from the liver Aldoramine: A drug that inhibits sodium/iodine cotransporter Thyromine: A drug that stimulates thyroglobulin production Identify the drug(s) that would be successful in treating hyperthyroidism and hypothyroidism, and explain why and how they…
You work for a pharmaceutical company where you are assigned the task of creating new drug therapies to treat thyroid disorders such as hyperthyroidism (high levels of T3 and T4) and hypothyroidism (low levels of T3 and T4). Your team has designed a few drugs, and your job is to identify which drug(s) would be successful in treating thyroid disorders based on your knowledge of thyroid hormone synthesis. Below is the list of drugs your team designed (all of these are hypothetical drugs). Please identify the drug(s) that would be successful in treating hypothyroidism, and explain why and how they would be successful. Aldosine: A drug that inhibits production of angiotensinogen from the liver Aldoramine: A drug that inhibits sodium/iodine cotransporter Thyromine: A drug that stimulates thyroglobulin production Peroxidine: A drug that inhibits thyroid peroxidase from functioning Cimigine: A drug that inhibits potassium/iodine cotransporter Iodimine: A drug that inhibits iodinase from…
Name two proteins that are effectors of the insulin signaling pathway in adipocytes, liver, or muscle cells. Explain how these effector proteins address the conditions that triggered insulin release.
What is the ligand(signaling molecule) in a(an) insulin signaling pathway and what causes this ligand to be sent out?
A certain type of tumor results in the overproduction of glucagon. Researchers claim that treatment with insulin can counteract the effects of the excess glucagon . Provide reasoning to justify the researchers' claim.
A woman affected by type I (insulin-dependent) diabetes miscalculates and injects herself with too much insulin. She soon begins to feel confused and sluggish. She calls for medical assistance and injects herself with the glucagon her doctor prescribed for such an emergency. When an ambulance arrives, she is given dextrose ( a sugar) intravenously. How did the excess insulin cause her symptoms. How did the glucagon injection and the intravenous sugar help reverse them?
What happens to the insulin-secreting capacity of a type 2 diabetic placed on insulin therapy earlier than recommended? Can the external supply of insulin improve the functional capacity of the insulin-secreting cells, to some extent by providing some rest to these cells? Is inhaled insulin a suitable substitute for injectable insulin? Is there, or will there soon be, insulin in the form of a tablet?
What are the steps involved in synthesis of genetically engineered insulin.
ou work for a pharmaceutical company where you are assigned the task of creating new drug therapies to treat thyroid disorders such as hyperthyroidism (high levels of T3 and T4) and hypothyroidism (low levels of T3 and T4). Your team has designed a few drugs, and your job is to identify which drug(s) would be successful in treating thyroid disorders based on your knowledge of thyroid hormone synthesis. Below is the list of drugs your team designed (all of these are hypothetical drugs). Aldosine: A drug that inhibits production of angiotensinogen from the liver Aldoramine: A drug that inhibits sodium/iodine cotransporter Thyromine: A drug that stimulates thyroglobulin production Identify the drug(s) that would be successful in treating hyperthyroidism and hypothyroidism, and explain why and how they would be successful.
Blood levels of the readily available fuel, glucose, are tightly regulated by two chemical messengers. One of these, called insulin, decreases blood glucose. The other chemical messenger, called glucagon, increases blood glucose. Both chemical messengers are present at varying levels in the blood at all times. From the choices below, select all of the events that you think will happen in response to a decrease in blood glucose. Select all that apply. > View Available Hint(s) V Insulin levels increase O Insulin levels decrease OGlucagon levels increase V Glucagon levels decrease O Blood glucose levels begin to increase O Blood glucose levels continue to decrease O Blood glucose levels remain unchanged