Chemistry
Chemistry
10th Edition
ISBN: 9781305957404
Author: Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher: Cengage Learning
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  1. Using this information and the image provided, describe the reaction catalyzed by an esterase and classify it as one of the 6 classes of enzymes. 
  2. The insert also tells you that Enalaprilat (the active form of Enalapril) targets angiotensin-converting enzyme (ACE), which cleaves the blood-pressure regulating peptide angiotensin I. The active form of the drug looks very similar to the endogenous substrate of the enzyme ACE.  Based on this information, what type of interaction is occurring between Enalaprilat and ACE?  Propose how the presence of Enalaprilat changes the overall reaction. 
  3.  
ОНО
-N HN-
Enalapril
Esterase
ОНО
CON
-N HN-
Enalaprilat
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Transcribed Image Text:ОНО -N HN- Enalapril Esterase ОНО CON -N HN- Enalaprilat
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