Using the information in the Reading file part II and textbook, answer the following questions: Whales possess vestigial organs in the form of pelvic girdle and hind limb bones. How would you explain this? How can you explain that, while forelimbs of bats and human arms are used for vastly different purposes, they do have similar anatomy? PART III. BIOINFORMATICS AND GENE MODIFICATION EVIDENCE SICKLE CELL ANEMIA: GENETICS AND EVOLUTION Circle the mutation in DNA of the sickle-cell beta-globin gene fragment in the table below: Wild-type beta-globin gene fragment C A C G T A G A C T G A G G A C T C Sickle-cell beta-globin gene fragment C A C G T A G A C T G A G G A C A C Transcribe beta-globin DNA into mRNA. Note: DNA is already arranged in triplet sets (below). Translate mRNA codons into amino acids of hemoglobin protein sequence using the chart on page 3. Wild-type beta-globin gene fragment C A C G T A G A C T G A G G A C T C Transcription produces mRNA fragment: Translation produces wild-type beta-globin polypeptide fragment: Sickle-cell beta-globin gene fragment C A C G T A G A C T G A G G A C A C Transcription produces mRNA fragment: Translation produces mutant beta-globin polypeptide fragment:
Using the information in the Reading file part II and textbook, answer the following questions:
- Whales possess vestigial organs in the form of pelvic girdle and hind limb bones. How would you explain this?
- How can you explain that, while forelimbs of bats and human arms are used for vastly different purposes, they do have similar anatomy?
PART III. BIOINFORMATICS AND GENE MODIFICATION EVIDENCE
- SICKLE CELL ANEMIA: GENETICS AND EVOLUTION
Circle the mutation in DNA of the sickle-cell beta-globin gene fragment in the table below:
|
Wild-type beta-globin gene fragment |
C A C G T A G A C T G A G G A C T C |
|
Sickle-cell beta-globin gene fragment |
C A C G T A G A C T G A G G A C A C |
Transcribe beta-globin DNA into mRNA. Note: DNA is already arranged in triplet sets (below).
Translate mRNA codons into amino acids of hemoglobin protein sequence using the chart on page 3.
|
Wild-type beta-globin gene fragment |
C A C |
G T A |
G A C |
T G A |
G G A |
C T C |
|
Transcription produces mRNA fragment: |
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Translation produces wild-type beta-globin polypeptide fragment: |
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Sickle-cell beta-globin gene fragment |
C A C |
G T A |
G A C |
T G A |
G G A |
C A C |
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Transcription produces mRNA fragment: |
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Translation produces mutant beta-globin polypeptide fragment: |
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