Using the information below, calculate the percentage w/V of lidocaine (MM (234-34 g/mol) in Lignocaine Oral Topical Solution. Show your reasoning clearly and record your final answer to three significant figures. dire Assay - "Transfer an accurately measured volume of Oral Topical Solution, equivalent to about 150 mg of lidocaine, to a 125 mL conical flask, and protect from atmospheric moisture with a stopper fitted with a tube containing Lidocaine silica gel. Add 20 mL of glacial acetic acid and 2 drops of crystal violet TS. Titrate immediately with 0.1 M perchloric acid VS to a blue endpoint. Perform a blank titration, and make the necessary correction." Results: • Amount of topical solution measured = 7.5 mL • Concentration HCIO, = 0.09998 M Volume titrated 6.99 mL Volume blank titration = 0.65 mL

Chemistry: The Molecular Science
5th Edition
ISBN:9781285199047
Author:John W. Moore, Conrad L. Stanitski
Publisher:John W. Moore, Conrad L. Stanitski
Chapter13: The Chemistry Of Solutes And Solutions
Section: Chapter Questions
Problem 36QRT
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Using the information below, calculate the percentage w/V of lidocaine (MM (234-34 g/mol) in
Lignocaine Oral Topical Solution. Show your reasoning clearly and record your final answer to three
significant figures.
Assay - "Transfer an accurately measured volume of Oral Topical Solution,
equivalent to about 150 mg of lidocaine, to a 125 mL conical flask, and
protect from atmospheric moisture with a stopper fitted with a tube containing
silica gel. Add 20 mL of glacial acetic acid and 2 drops of crystal violet TS. Titrate immediately with
0.1 M perchloric acid VS to a blue endpoint. Perform a blank titration, and make the necessary
Lidocaine
correction."
Results:
• Amount of topical solution measured = 7.5 mL
Concentration HCIO, = 0.09998 M
Volume titrated = 6.99 mL
Volume blank titration = 0.65 mL
Transcribed Image Text:Using the information below, calculate the percentage w/V of lidocaine (MM (234-34 g/mol) in Lignocaine Oral Topical Solution. Show your reasoning clearly and record your final answer to three significant figures. Assay - "Transfer an accurately measured volume of Oral Topical Solution, equivalent to about 150 mg of lidocaine, to a 125 mL conical flask, and protect from atmospheric moisture with a stopper fitted with a tube containing silica gel. Add 20 mL of glacial acetic acid and 2 drops of crystal violet TS. Titrate immediately with 0.1 M perchloric acid VS to a blue endpoint. Perform a blank titration, and make the necessary Lidocaine correction." Results: • Amount of topical solution measured = 7.5 mL Concentration HCIO, = 0.09998 M Volume titrated = 6.99 mL Volume blank titration = 0.65 mL
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