Unmyelinated axons conduct action potentials without decrement, but when myelinated axons lose myelin in demyelinating diseases such as multiple sclerosis, conduction of action potentials is blocked. Why?

what are Axons coated with this electrically insulating substance have higher conduction velocities compared to neurons without it?

Explain how an action potential is propagated down an axon in continuous conduction. Why is saltatory conduction faster than continuous conduction?

1. If you block calcium channels on an axon, which will not occur? A) exocytosis of neurotransmitter B) repolarization phase of the action potential C) depolarization phase of the action potential D) hyperpolarization phase of the action potential E) graded potential

Compare and contrast the neuroglial cells that form the myelin sheaths in both the CNS and the PNS?

Your best friend, Reg, was walking through the forest when they found some particular delicious looking mushrooms.  Thinking they know all about mushroom safety, they promptly set up their camp stove and cooked and ate a mushroom omelette.  Shortly afterwards, they begin to feel body numbness, blurred vision, and lack of coordination. An unknown toxin from the mushroom is affecting the action potential (AP)! Using your knowledge of action potentials (M1L3), please answer the following questions below.  Be sure to clearly label the different parts. Part A. Describe the processes that take place during AP initiation and identify the channels involved. Part B. If the toxin is making it harder to initiate an AP, what might be happening to the voltage-gated channels ? Part C. What do you predict lowering the resting membrane membrane potential (making it more negative) would do to AP initiation? Explain your reasoning.