True or false PFC's (perfluorinated hydorcarbon chains) can supply oxygen but do not dissolve well in blood plasma. In order to use PCF's as a blood substitute patients must breathe 70-100% oxygen through a mask. PFC's are eventually removed by the body through exhalation.
True or false
PFC's (perfluorinated hydorcarbon chains) can supply oxygen but do not dissolve well in blood plasma.
In order to use PCF's as a blood substitute patients must breathe 70-100% oxygen through a mask.
PFC's are eventually removed by the body through exhalation.
Hemoglobin is the oxygen carrier of the blood. However, hemoglobin has a short lifespan and it splits in half in the plasma and it is rapidly cleared by the kidneys. Another problem is that hemoglobin binds much more tightly to oxygen, and fails to give up to needy tissues. Therefore, some engineers tried to generate chemical compounds such as perfluorinated hydrocarbon chains (PFCs) to overcome all of these shortcomings of hemoglobin. PFCs have a long shelf life, and no biological contamination.
a.
PFCs can hold large amounts of dissolved oxygen, much more than plasma. In one study, researchers completely submerged pre-mature newborns of mice respired well in liquid PFCs. But liquid ventilation of adult mice led to severe lung dysfunction.
PFCs have a serious shortcoming that they don’t dissolve in plasma. Therefore, the statement “PFC's (perfluorinated hydrocarbon chains) can supply oxygen but do not dissolve well in blood plasma is true.
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