Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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true or false NADH and FADH2 deliver the same number of electrons to the ETC?
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- ATP, like ADP and AMP, is a competitive inhibitor of NADH binding to malate dehydrogenase. Provide a structural explanation for this inhibition.arrow_forwardProcesses taking place in the mitochondrion convert the chemical potential energy of NADH into the chemical potential energy of ATP. A proton concentration gradient (Δ[H+]) is part of this process. Describe exactly where this gradient is located, and how the gradient is produced. In terms of the gradient, where is the higher [H+] and where is the lower [H+]?arrow_forwardWhat is the significance of NADH and FADH2 in ET/OP?arrow_forward
- Follow the two carbon atoms that enter the citric acid cycle (C₂). Are the two CO₂ molecules given off in one turn of the citric acid cycle composed of the same 2 carbon atoms that entered the cycle? NADH + H+ NAD+ H HỌ—C—COO- H₂C-COO- °↑ 7 FADH₂ 0 C-C00 H₂C-COO- Oxaloacetate Malate HC-COO- -OOC-CH Fumarate FAD Succinate H₂C-COO H₂C-COO CH,CO—S-CoA Acetyl coenzyme A GTP COA GDP COA H₂C-COO- HỌ–C–COO- H₂C-COO- Citrate H₂C-COO- Isocitrate HC-COO- HO–C–COO H e T CO₂ Succinyl COA H₂C-COO- CO₂ a-Ketoglutarate CoA H₂C-CO-S-CoA H₂C-COO H₂C 0-C-COO- NAD+ NADH + H+ NAD+ NADH + H+arrow_forwardThe energy stored in one molecule of NADH is used to synthesize how many molecules of ATP?arrow_forwardUnder standard conditions, will the following reactions proceed spontaneously as written? (1) Fumarate + NADH + H+ (2) succinate + NAD+ Cyto a (Fe²+) + cyto b (Fe³+) = cyto a (Fe³+) + cyto 6 (Fe²+) barrow_forward
- From the complete oxidation of glucose (glucose → 6CO2), how many total NADH electron carriers are produced?arrow_forwardIf α-ketoglutarate is removed from TCA cycle and used to make glutamate, how many of each of the cofactors (not intermediates) and high energy molecules in the TCA cycle are lost? How much ATP does this equate to (NADH = 2.5 ATP, FADH2 = 1.5 ATP)?arrow_forwardWhen the cells of our body are in dire need to synthesize Ribose 5 phosphate and it has already enough supply of NADPH, reverse non oxidative pathway of the HMP shunt pathway takes place. If the cell has 10 glucose 6 phosphate molecules, how many of these would be converted to Fructose 6 phosphate and how many to form glyceraldehyde 3 phosphate respectively to synthesize maximum number of Ribose 5 phosphate? 8:2 2:8 4:6 6:4arrow_forward
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