This question uses the same experimental setup as in Question 1 and the same modification of the attached figure (Figure 2.5 of your textbook). The modification is that the KCL solutions in the middle panel are replaced with NaCl solutions (1 mM on the left or inside and 10 mM on the right or outside). What would initially happen if the membrane was made permeable to Na+? (A) Lure D A Inside 1 mM KQ Voltmotor V=0 elle Outside 1 mM KCI Termeable to K* No net flux of K* K' lon (B) Initial conditions ● lo 6 Inside 10 πιΜ KCl Initially V=0 очен Outside 1 mM KCI Net flux of K from inside to outside At equilibrium V in-out= -38 my a ✪ m O Inside Outside 10 mM KC 1 mM ka Flux of K* from inside to outside balanced by opposing membning potential Membrane potential V₁ (mv) 8 -116 100 -2 [K' (MM) 10 108 Na+ would move up its concentration gradient from the left (inside) to the right (outside) compartment. Na+ would move down its concentration gradient from the right (outside) to the left (inside) compartment. Na+ would not move because it is at equilibrium. Slope 58 mV per tenfold change in K gradient Na+ would not move because it has a valence (i.e.. charge) of 1+. 0

Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter3: The Plasma Membrane And Membrane Potential
Section: Chapter Questions
Problem 2SQE: One of the important uses of the Nernst equation is in describing the flow of ions across plasma...
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Question
This question uses the same experimental
setup as in Question 1 and the same
modification of the attached figure (Figure 2.5
of your textbook). The modification is that
the KCL solutions in the middle panel are
replaced with NaCl solutions (1 mM on the
left or inside and 10 mM on the right or
outside). What would initially happen if the
membrane was made permeable to Na+?
(A)
Lure
D
A
Inside
1 mM KQ
Voltmotor
V=0
elle
Outside
1 mM KCI
Termeable to K*
No net flux of K*
K' lon
(B) Initial conditions
●
lo
6
Inside
10 πιΜ KCl
Initially
V=0
очен
Outside
1 mM KCI
Net flux of K
from inside
to outside
At equilibrium
V
in-out= -38 my
a
✪
m
O
Inside
Outside
10 mM KC 1 mM ka
Flux of K* from inside to
outside balanced by opposing
membning potential
Membrane potential
V₁ (mv)
8
-116
100
-2
[K' (MM)
10
108
Na+ would move up its concentration gradient
from the left (inside) to the right (outside)
compartment.
Na+ would move down its concentration gradient
from the right (outside) to the left (inside)
compartment.
Na+ would not move because it is at equilibrium.
Slope 58 mV per
tenfold change in
K gradient
Na+ would not move because it has a valence (i.e..
charge) of 1+.
0
Transcribed Image Text:This question uses the same experimental setup as in Question 1 and the same modification of the attached figure (Figure 2.5 of your textbook). The modification is that the KCL solutions in the middle panel are replaced with NaCl solutions (1 mM on the left or inside and 10 mM on the right or outside). What would initially happen if the membrane was made permeable to Na+? (A) Lure D A Inside 1 mM KQ Voltmotor V=0 elle Outside 1 mM KCI Termeable to K* No net flux of K* K' lon (B) Initial conditions ● lo 6 Inside 10 πιΜ KCl Initially V=0 очен Outside 1 mM KCI Net flux of K from inside to outside At equilibrium V in-out= -38 my a ✪ m O Inside Outside 10 mM KC 1 mM ka Flux of K* from inside to outside balanced by opposing membning potential Membrane potential V₁ (mv) 8 -116 100 -2 [K' (MM) 10 108 Na+ would move up its concentration gradient from the left (inside) to the right (outside) compartment. Na+ would move down its concentration gradient from the right (outside) to the left (inside) compartment. Na+ would not move because it is at equilibrium. Slope 58 mV per tenfold change in K gradient Na+ would not move because it has a valence (i.e.. charge) of 1+. 0
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