This image is showing the conformations of ubiquitin superimposed. What do the structures in this figure tell us about the dynamics of enzymes? Discuss the limitations of crystal structures in the analysis of proteins. What are the benefits? What are the advantages of NMR structures?

Q: (c) Outline how you would investigate whether BCMAP would be an effective inhibitor for the protein…

A: Inhibitors are the molecules that slow down or completely block the protein activity of molecules,…

Q: NH2 -NH он NH2 HO. OH OH O NH2 NH но OH но HN HO. HN NH2 NH OH ÔH HN. он NH HN NH2

A: Oligopeptides are those peptides which consists of 2 to 20 amino acids.

Q: Show the complete steps and products of the Haworth Projection structure of the following…

A: Sorbose and mannose are hexose monosaccharides. Sorbose is a ketose while mannose is an aldose. A…

Q: Chymotrypsin is a pH dependent protein. Enzymatic activity is the greatest between pH=7.0 to pH=8.5.…

A: Chymotrypsin is a protease that is secreted by the pancreas. It cleaves the peptide bond next to the…

Q: Polypeptide folding is often mediated by other proteins called chaperones. Describe how a mutant…

A: Chaperones are proteins that guide proteins along the proper pathways for folding. They protect…

Q: "All enzymes are protein but not all protein are enzymes" Discuss and prove this concept. Cite…

A: An enzyme is a biocatalyst that increases the rate of chemical reaction without itself being changed…

Q: All three types of biopolymers are set from the building blocks with similar types of chemical…

A: Proteins are polymers of amino acids attached through peptide bonds. Proteins have four different…

Q: Which nuclear isotope used in protein NMR spectroscopy is the most sensitive to detect? Briefly…

A: NMR Spectroscopy is used to study the structure and composition of biomolecules like proteins. Here…

Q: Using condensed structures, supply an outline of the mechanism for the formation of Gly-Gly in the…

A: During peptide bond formation the carboxylic acids and primary or secondary - amines do not undergo…

Q: The structures of the amino acids leucine and isoleucine are shown: H N-C-C CH₂ CH HỌC CH, Leucine H…

A: A protein's function depends on its structure. There are four levels of protein structure: primary,…

Q: Propose a method to determine the size and basic structure of chymotrypsin for the purpose of…

A: Any matter on the planet consists of atoms linked by interatomic bonds. The properties of the matter…

Q: Consider the oligopeptide whose structure is shown below: How many peptide bonds are there? Give…

A: please note that we are supposed to write only first 3 sub parts of a question. We request you to…

Q: When calculating the order of a reaction, the enzyme doesnot appear in the equation. Explain.

A: Enzyme are the biocatalysts which increase the rate of biochemical reaction by decreasing the…

Q: Are the amino acid residues at the active site need to be in close proximity to one another…

A: Enzymes are the catalysts that catalyze biochemical reactions. These are proteinaceous in nature as…

Q: Oligosaccharides are short sugar chains that can become covalently linked to proteins and lipids…

A: The answer is serine

Q: Denatured protein is in a low energy state. What sort of explanation can you use to rationalize that…

A: Denaturation of protein: When proteins are denaturized, they lose the quaternary, tertiary, and…

Q: 3CLpro is a cysteine protease, which are among the most common proteases in biochemistry, however…

A: The 3 dimensional conformation of a biomolecule is highly specific and vital to its function,…

Q: Discuss the behavior of enzymes as described by the Michaelis-Menten Equation

A: Enzymes are proteins with the capability to accelerate the rate of a biochemical reactions. Enzymes…

Q: You are studying a catalytic protein which contains two ion clusters, one cluster contains 2 Cu+3…

A: Proteins are the biomolecules that are building blocks of the body. Proteins are made up of amino…

Q: Proteins are thermodynamically unstable. The ΔG of the hydrolysis of proteins is quite negative, yet…

A: Proteins are macromolecules made up of individual amino acid monomers. Proteins are synthesized…

Q: If an enzyme carries out acid-base catalysis, which of the following amino acids (in its…

A: Proteins are critical to the continued functioning of life on Earth. The vast majority of chemical…

Q: Cysteine is converted to cystine which is readily transported into mammalian cells. In the cells,…

A: A disulfide bond (also called an S-S bond) forms between two cysteine residues due to oxidation of…

Q: Describe the three main classes of glycoproteins and explain their biochemical roles.

A: Introduction   Glycoproteins are proteins that contain carbohydrates attached to amino acid…

Q: Are proteins and enzyme the same in its structure and function. Why? Explain and provide an example…

A: Introduction: The human body contains a number of cells that perform various functions with the help…

Q: ou have been researching two additional methyltransferase enzymes that catalyze the same reaction.…

A: For a one-substrate enzyme-catalyzed reaction, the Michaelis-Menton equation shows the quantitative…

Q: In the fungus Neurospora, some mutants were obtained that lacked activity for a certain enzyme. The…

A: Biomolecules are organic compounds found in living organisms. All living organism will have these…

Q: Eukaryotic protein X has one proline residue and two cysteine residues. The proline needs to be in…

A: Eukaryotic protein : It is usually the cytoplasmic ribosomes that translate nuclear genes. several…

Q: Idris has successfully extracted enzymatic proteins from the fish viscera (intestines and stomach).…

A: The first step after crude protein isolation from any sample is the quantification of the total…

Q: Imagine the main chain of a protein bends back on itself, so that two amino acid residues R, and R,…

A: Salt bridge is a bond between amino acids which carry opposite charges. The opposite charges exert…

Q: Two common methods of denaturing proteins in the lab are to increase the temperature and/or add…

A: Proteins are biomolecules with diverse biological roles. The function of a protein depends on its…

Q: Include a couple of paragraphs about Alkaline Phosphatase. Make sure you describe the following: a.…

A: A small pH range is required for the majority of enzymes to operate. When the pH is changed, the…

Q: NH он NH2 LOH OH O NH, NH но HN OH HN NH2 NH он ÔH HN. OH NH HN NH2

A: Oligopeptides are also referred as peptide. Oligopeptide consists of 2 to 20 amino acids.

Q: Lactose is the sugar component of milk, which is why it is referred to as "milk sugar." It is…

A: Carbohydrates are the most essential biomolecule and the primary source of energy in many organisms.…

Q: Experimental results describing a protein's amino acid composition are useful for estimating the…

A: Proteins are high molecular weight polymers of amino acid residues linked together via peptide…

Q: Mechanistic probes often require the use of an electrophilic functional group to interact with an…

A: A nucleophile is a chemical species that is negatively charged or has a high electron density or a…

Q: The following reaction scheme shows the states of the amino acid hisitdine. Histidine has three…

A: Histidine is an amino acid that is used for the purpose of protein biosynthesis. It comprises an…

Q: Which way is more common practice to characterize the strength of a binding reaction between a…

A: Answer : the more common practice to characterize the strength of a binding reaction between a…

Q: Prepare a schematic diagram and present it as though it were a Figure in a publication (scientific…

A: Binding of ligand to receptor or protein can be specific and non-specific. For the genuity of the…

Q: Comment on why the feature ~210 nm in Circular Dichroism and Infrared spectroscopy  is useful for…

A: Circular dichroism spectroscopy (CD) is a fundamental insightful method used to investigate…

Q: Serine is an uncharged, polar amino acid (below and left). Threonine (below and right) is another…

A: Amino acids are the building blocks of proteins which are composed of amino group (NH3+), carboxyl…

Q: Some proteins induce cell death and some proteins inhibit it. What is the biological relevance of…

A: The cells of a multicellular creature are individuals from a profoundly coordinated network. The…