This aldol reaction product: Thermodynamic enolate OH was made using a (circle one): Kinetic enolate

Draw the step by step mechanism

1. Provide the mechanism of the reaction shown in the picture. 2. Explain why it cannot be done in basic conditions. 3. Why is the enol tautomer favored over the keto tautomer?

In the presence of a base which of the following will not form an enolate?

Draw the structure of the major aldol product (prior to possible dehydration) of the following reaction. CH3 O CH3 dilute aqueous NaOH 0-5° CH3 H • You do not have to consider stereochemistry. • If no reaction occurs, draw the organic starting material. + Sn ? ChemDoodle

Draw the organic reagents necessary to synthesize the following compound by an aldol condensation.

For the “crossed” aldol reaction that lead to product C, did the kind of base used make any difference to the reaction outcome? If so, what happened?  What is different between KOH and LDA Butyraldehyde + Benzaldehyde + Ethanol + KOH or LDA Butyraldehyde + Benzaldehyde + Ether + KOH or LDA

Draw a complete stepwise mechanism for the aldol self-condensation reaction shown below. You must show the structures of all intermediates and indicate electron flow with curly arrows