There are several feeder pathways that lead other monosaccharides into glycolysis. Below are the reactions for D-mannose: CHEMICAL EQUATION Mannose + ATP → Mannose 6-phosphate ENZYME RESPONSIBLE AG° (kJ/mol) hexokinase -15.7 phosphomannose isomerase +2.5 Mannose 6-phosphate → Fructose 6-phosphate The AG° values for the full glycolytic pathway can be found in the following table. The reported values are for ONE MOLE of the appropriate reactant being converted into product. Step AG (/mol) Step AG" (/mol) 1 -16.7 6 +6.3 2 +1.7 7 -18.5 3 -14.2 8 +4.4 4 +23.8 9 +7.5 5 +7.5 10 -31.4 مل

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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a.What is the overall ΔG°ʹ for glycolysis when starting with mannose rather than glucose?

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b.

There are several feeder pathways that lead other monosaccharides into glycolysis. Below are the
reactions for D-mannose:
CHEMICAL EQUATION
Mannose + ATP → Mannose 6-phosphate
ENZYME RESPONSIBLE
AG° (kJ/mol)
hexokinase
-15.7
phosphomannose isomerase
+2.5
Mannose 6-phosphate → Fructose 6-phosphate
The AG° values for the full glycolytic pathway can be found in the following table. The reported values
are for ONE MOLE of the appropriate reactant being converted into product.
Step
AG (/mol)
Step
AG" (/mol)
1
-16.7
6
+6.3
2
+1.7
7
-18.5
3
-14.2
8
+4.4
4
+23.8
9
+7.5
5
+7.5
10
-31.4
مل
Transcribed Image Text:There are several feeder pathways that lead other monosaccharides into glycolysis. Below are the reactions for D-mannose: CHEMICAL EQUATION Mannose + ATP → Mannose 6-phosphate ENZYME RESPONSIBLE AG° (kJ/mol) hexokinase -15.7 phosphomannose isomerase +2.5 Mannose 6-phosphate → Fructose 6-phosphate The AG° values for the full glycolytic pathway can be found in the following table. The reported values are for ONE MOLE of the appropriate reactant being converted into product. Step AG (/mol) Step AG" (/mol) 1 -16.7 6 +6.3 2 +1.7 7 -18.5 3 -14.2 8 +4.4 4 +23.8 9 +7.5 5 +7.5 10 -31.4 مل
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