The T-cell co-receptor CD4 interacts with _______ bound to the surface of _______: a. MHC class I; antigen-presenting cells b. MHC class I; T cells c. MHC class II; antigen-presenting cells d. MHC class II; T cells e. none of the above.
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The T-cell co-receptor CD4 interacts with _______ bound to the surface of _______: |
a. MHC class I; antigen-presenting cells |
b. MHC class I; T cells |
c. MHC class II; antigen-presenting cells |
d. MHC class II; T cells |
e. none of the above. |
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- Which of the following statements about T cells is false? a. Helper T cells release cytokines while cytotoxic T cells kill the infected cell. b. Helper T cells are CD4+, while cytotoxic T cells are CD8+. c. MHC II is a receptor found on most body cells, while MHC I is a receptor found on immune cells only. d. The T cell receptor is found on both CD4+ and CD8+ T cells.Explain why each choice (a-d) is correct or incorrect. In order for an antigen to activate or sensitize a T helper cell, the antigen must be a. coated with antibodies b. displayed on the surface of an APC along with MHC antigens c. displayed on the surface of another T cell with IgD antibodies d. partly digested by a natural killer cellWhich of the following is not used as a treatment for autoimmune diseases? Select one: A. Anti-IL2 receptor B. Anti-CD4 C. Anti-MHC D. Anti-CCR5 E. Anti-T cell receptor
- An MHC class II/antigen complex on the surface of an antigen-presenting cell (APC) binds to a T-cell receptor. What results from this interaction? Select one: a. Other immune cells are stimulated to respond to the antigen. b. Other immune cells are inhibited. c. The T cell responds by directly destroying the APC. d. The antigen is phagocytized by the T cell.Which of the following interactions will NOT provoke an immune response? A. Endogenous antigen + MHC Class I + TCR + CD 8+ B. Exogenous antigen + MHC Class II + TCR + CD 4+ C. Exogenous antigen + MHC Class II + BCR D. Endogenous antigen + MHC Class I + BCRThe binding groove of endothelial protein C receptor (EPCR) binds to _____ and presents them to _____. a. phosphoantigens; Vγ9:Vδ2 T cells b. MIC-A or MIC-B proteins; NK cells c. sulfatides; Vγ:Vδ1 T cells d. phospholipids; Vγ4:Vδ5 T cells e. lipid antigens; Vα24–Jα18:Vβ11 NKT cells.
- Which of the following statements regarding CD4 is incorrect? a. MHC class II molecules present antigens to CD4 T cells. b. CD4 is the receptor used for HIV entry into CD4 T cells. c. CD4 is made up of two separate membrane-bound chains. d. Late in the progression of an HIV infection, the number of CD4 T cells in the circulation diminishes. e. CD4 is referred to as a T-cell co-receptor.The zone of contact between the T cell and a pathogen-infected cell is called a(n) Select one: a. immunoreceptor tyrosine-based activation motif (ITAM) b. polarization C. cross-presentation center d. granuloma e. immunological synapseWhich of the following is not important in the antiviral innate immune response?a. interferonsb. natural killer cellsc. complementd. microphages
- Which of the following is part of the second line of defense against pathogens?a. skin b. mucus membranesc. lysozyme in tears d. phagocytes Which of the following does NOT have MHC class II molecules on the surface of their cell membranes? a. Macrophages.b. Dendritic cells.c. B cells.d. Helper T cells.A number of minor cancerous cells and infected viruses, such as Epstein Barr (EBV), are able to go undetected by cytotoxic T cell degradation by what possible mechanism? a. the production of normal class I MHC molecule b. helper T cell activation c. the deactivation of the complement system d. tumor antigen expression e. the production of the class II major histocompatability (MHC) moleduleWhich of the following pairs is mismatched? a. plasma cell: mediation of phagocytosis and killing of microorganisms in the plasma b. megakaryocyte: formation of platelets c. dendritic cell: activation of adaptive immune responses d. natural killer cell: develops from a common lymphoid progenitor e. neutrophil: formation of pus f. regulatory T cell: inhibition of T-cell activity.