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The reaction in gluconeogenesis catalyzed by Glyceraldehyde-3-phosphate dehydrogenase (GADPH) requires NADH. What are potential sources of cytosolic NADH? i. The conversion of Malate to Oxaloacetate (catalyzed by cytosolic malate dehydrogenase (MDH)) ii. The conversion of 1,3 Biphosphoglycerate to Glyceraldehyde-3-phosphate (catalyzed by Glyceraldehyde 3 phosphate dehydrogenase (GAPDH)) iii. The conversion of Lactate to Pyruvate (catalyzed by Lactate dehydrogenase (LDH)) iv. The conversion of Oxaloacetate to Malate (catalyzed by mitochondrial malate dehydrogenase (MDH)) Only i and ii are correct Only i is correct Only i and iii are correct Only ii is correct Only i, ii, and iii are correct All four (i-iv) are correct

The reaction in gluconeogenesis catalyzed by Glyceraldehyde-3-phosphate dehydrogenase (GADPH) requires NADH. What are potential sources of cytosolic NADH? i. The conversion of Malate to Oxaloacetate (catalyzed by cytosolic malate dehydrogenase (MDH)) ii. The conversion of 1,3 Biphosphoglycerate to Glyceraldehyde-3-phosphate (catalyzed by Glyceraldehyde 3 phosphate dehydrogenase (GAPDH)) iii. The conversion of Lactate to Pyruvate (catalyzed by Lactate dehydrogenase (LDH)) iv. The conversion of Oxaloacetate to Malate (catalyzed by mitochondrial malate dehydrogenase (MDH)) Only i and ii are correct Only i is correct Only i and iii are correct Only ii is correct Only i, ii, and iii are correct All four (i-iv) are correct

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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The reaction in gluconeogenesis catalyzed by Glyceraldehyde-3-phosphate dehydrogenase (GADPH) requires NADH. What are potential sources of cytosolic NADH? i. The conversion of Malate to Oxaloacetate (catalyzed by cytosolic malate dehydrogenase (MDH)) ii. The conversion of 1,3 Biphosphoglycerate to Glyceraldehyde-3-phosphate (catalyzed by Glyceraldehyde 3 phosphate dehydrogenase (GAPDH)) iii. The conversion of Lactate to Pyruvate (catalyzed by Lactate dehydrogenase (LDH)) iv. The conversion of Oxaloacetate to Malate (catalyzed by mitochondrial malate dehydrogenase (MDH)) O Only i and ii are correct Only i is correct Only i and iii are correct Only ii is correct Only i, ii, and iii are correct O All four (i-iv) are correct
Transcribed Image Text:The reaction in gluconeogenesis catalyzed by Glyceraldehyde-3-phosphate dehydrogenase (GADPH) requires NADH. What are potential sources of cytosolic NADH? i. The conversion of Malate to Oxaloacetate (catalyzed by cytosolic malate dehydrogenase (MDH)) ii. The conversion of 1,3 Biphosphoglycerate to Glyceraldehyde-3-phosphate (catalyzed by Glyceraldehyde 3 phosphate dehydrogenase (GAPDH)) iii. The conversion of Lactate to Pyruvate (catalyzed by Lactate dehydrogenase (LDH)) iv. The conversion of Oxaloacetate to Malate (catalyzed by mitochondrial malate dehydrogenase (MDH)) O Only i and ii are correct Only i is correct Only i and iii are correct Only ii is correct Only i, ii, and iii are correct O All four (i-iv) are correct
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