### Understanding the Michaelis Constant (KM)In the study of enzyme kinetics, the Michaelis constant (KM) for a substrate is a crucial parameter that defines the substrate concentration at which the reaction rate is at half of its maximum. This concept can be expressed in a few different ways:a. **k-1/k2**: This option suggests a relation involving reaction rate constants. Typically, KM is more directly related to the breakdown and formation of enzyme-substrate complexes rather than a simple ratio of these constants.b. **Vmax/2**: This option is incorrect as KM specifically refers to substrate concentration, not the velocity directly.c. **[S] at Vmax/2**: This is the correct representation. KM is defined as the substrate concentration ([S]) at which the reaction velocity is half of Vmax (maximum velocity).Understanding KM helps in determining the affinity of an enzyme for its substrate; a lower KM indicates a higher affinity, meaning less substrate is needed to reach half of the maximum reaction rate.

Answered: Image /qna-images/answer/2dec64ca-be04-45f5-8216-eee14f993cbb.jpg

Answered: The KM for a substrate is equal to a.…

Science

Chemistry

The KM for a substrate is equal to a. k-1/k2. b. Vmax/2. c. [S] at Vmax/2.

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

See similar textbooks

Related questions

Q: 2-Van der Waals constant b of helium is 24 mL mol-1. Find molecular diameter of helium. 2.67 X10-8…

A: 'b' is also known as excluded volume. It is four times then the volume of a 1 mole of molecules.

Q: 22. Find the Miller indices of a plane that makes intercepts on a, b and c axes equal to 4A, 6A and…

A: Miller indices are a set of integers (h, k, l) which are used to describe a given plane in a…

Q: Electronic semi conductor In a direct band gap semiconductor quantum well of 10 nm thickness…

A: In the direct bandgap semiconductor for the transition of an electron from the first excited state…

Q: GNO+UNt what volume of NH3 s, at Standard tempature Hz>5N2+ 6 Hz O 3. tempatire pressur e (STP), is…

Q: Phase-I sepera 1 11 Dipote-[ lon-Di Dispersi Hydroge N-H₂ O Surfacet CONESA adnesio Viscosit…

A: N2 (g) + 3H2 (g) ----> 2NH3 (g) Kc = 1.2

Q: The aluminum in a package containing 70. ft of kitchen foil weighs approximately 12 ounces. Aluminum…

A: Given the area of the aluminium foil, A = 70. ft2 mass of the aluminium foil, m = 12 ounces…

Q: In order to separate the components of a mixture that consists of iron dust, naphtalene and table…

A: Given: Mixture of iron dust, naphthalene and table salt.

Q: G: C,H,NO Hz ppm 650.31 7.262 858 645.88 7.212 46 392.56 4.384 230 386.81 4.320 218 m, 5H 174.25…

Q: Compatible Polymers A and B are to be blended to achieve a glass-transition temperature of 60 o C.…

Q: (4113011 5. A monoprotic acid (HA) with K, of 8.76 x 10 has a partition coefficient of 3.9 (favoring…

A: 5#(a): The organic solvent used for extraction is octanol. Given the partition coefficient, P = 3.9…

Q: Classify pure urea, H2NCONH2 fertilizer as NPK. Write your numerical answer in the order N, followed…

A: NPK ratio is basically the ratio by mass. The molar mass of urea is 60.06g/mol The molar mass of…

Q: 7. Beer's Law calibration Plot? Which of the following statements describe R? and its significance…

A: Beer᾿s Law : Decrease in intensity with thickness is directly proportional to concentration.…

Q: PPM

A: The correct answer about NMR spectrum is given below

Q: Home 101 Chem 101 X (274) (Letra) A Mi Me Esta D X X х app.101edu.co Unofficial Transcript... S…

A: To find the new concentration of the solution, we have to use the dilution equation in respect to…

Q: 05) Determine Assume the soil coefficient (log Koc). factor teem in your molecular structure is…

A: The objective of the question is to determine the soil coefficient (log Koc) using the given…

Q: 19. 8.24 atm/cm² to torr/ft

Q: How do you find the Ksp and solubility limit for Sr(IO3)2 given [IO3]=0.00879366 & [Sr]=0.00439683?

A: The answer to the following question is-

Q: 13. The presented scheme has flaws. What is/are the flaw/s? CH3 соон 1. Cl2, FeC, 2. KMNO.

A: Solution - First KMnO4 is used to oxidize the CH3 group into COOH which acts as a EWG. When Cl2 is…

Q: 1. You wish to determine the %concentration of a stock solution of brilliant blue FCF…

A: Let's say that the molar concentration of stock solution be 'X M'.

Q: Solution: Kso=1.41-10-11 The resistance of a saturated solution of PbSO4 (very insoluble salt) at…

Q: Potassium permanganate, KMnO4 is a deep purple solid and solutions of KMnO4 can be analyzed using…

A: The relation between percentage transmittance(%T) and Absorbance (A) is A=-log%T100 Convert the %T…

Q: tH2A chemist pReaped r pachadoad 5.04 of Ag NO, in wateR to make 350.0mb 4issolving of Sólution.…

Q: 2 > A sample of gas occupies a volume of 50.7 mL. As it expands, it does 123.5 J of work on its…

Q: Iraw The eneray degram for this mechaines n reacnlan. give he PeacNon is endo thermict. Label all…

A: Slowest step is the rate determining step or , r.d.s . Of the reaction. 1st step is the equilibrium…

Q: Quel-A Solulion is prepor al by aliluking1:76g of Nacog(97% Pure) in5ömL. of deionized water…

Q: the donor ConCentration Concentration is the acceptor the resulting Semiconductor would be the…

A: Calculate the donor and acceptor concentrations in the semiconductor. The concentration of the…

Q: 24. Change the following Miller indices: (210), (1 13), (011), (246) and (4 2 3) into Miller-Bravais…

A: Miller indices are a set of integers (h, k, l) which are used to describe a given plane in a…

Q: Figure 10-5 Br 4 5 ктот ви QOCH 3 6 @OCH3 K* -O*Bu CHзон heat А. В. с. Д. Е. L ОСН3 оснз LOCH 3

A: In the majority of the organic reactions, a mixture of products is obtained. In this mixture, some…

Q: Given Lugol’s solution (5% w/v) from http://www.labchem.com/tools/msds/msds/LC15675.pdf How is it…

A: I think it is categorised under category 2 which is not there in the options. You can cross check it…

Q: When KHCO3 is dissolved in water, how many particles will be in solution? Выберите один ответ: а. 3…

A: Given question is : When KHCO3 is dissolved in water, how many particles will be in solution ?…

Q: A certain saturated salution of Cas(POnz has [Catt]= P Oy 8 ] = 2,9 X10: What is the value of Kps…

A: Given, [Ca+2] = [PO43-] = 2.9 ×10-7 Ca(PO4)3 → Ca2+ + 3PO4

Q: What is the equivalent weight of the vehicle?

A: below.

Q: Which of the following affects the sedimentation of a particle in gradient ultracentrifugation?…

A: The rate of sedimentation is proportional to the 1) The difference in density between particles…

Q: Calculating mole fraction A solution is made by mixing 17. g of heptane (C₂H16) and 40. g of…

A: Given,The mass of heptane ( C7H16 ) = 17. gThe mass of chloroform ( CHCl3 ) = 40. g

Q: 2. In a certain polluted area, the partial pressure of NO gas was 8 pascal. The mixing ratio of NO…

A: Hii there, As there are multiple question posted. we are answering first question. If you need…

Q: Use [p + (dU/dV)T](dV/dT)P + [p + (dU/dV)T = T(dp/dT)V to find Cp - Cv for a van der Waals gas (p +…

Q: (c) Why calibration by area normalisation is used when assessing drug stability

A: When a chemical substance imparts a notable change in the physiological activity of an organism,…

Q: 4 parts I'm unsure of.

A: The sum factor associated with the provided quantity involves the addition of all the parameters.…

Q: Coivenat 2 CH₂₂Cl₂ (g) (Hy cg | + c clucg at Ke = 10.5 350 k I raction mixture was found to contain…

Q: For the following reaction 2 C₂H₂ (9) = C₂H4 (9) + C₁ H₂ (2) InKeq = A + + + P Which one of the…

Q: #3. Find PV = 77.0 m3 V' = 138 m3 P' = 42.0 kPaP = kPa #13. Some methane at 493 kPa gauge pressure…

A: Given : 1 m3 = 1000 L Volume (V) = 77.0 m3 = 77000 L Volume (V') = 138 m3 = 138000 L 1 KPa =…

Q: c. Use the table space below to calculate k by linear regression. . c(NiCl₂) (M) 0.273 0.2047 A…

Q: जाNen . 345M o! व्थप्बपc ureuk odd रच्चaजeन बनट कबछ व Rb 0R3.91x |00. The pH ०। गउ ज १cd +5 3. +. A.…

A: given :- molar concentration of acid = 0.345 M Kb = 3.91 x 10-10 To determine :- whether the pH…

Question

### Understanding the Michaelis Constant (KM)

In the study of enzyme kinetics, the Michaelis constant (KM) for a substrate is a crucial parameter that defines the substrate concentration at which the reaction rate is at half of its maximum. This concept can be expressed in a few different ways:

a. **k-1/k2**: This option suggests a relation involving reaction rate constants. Typically, KM is more directly related to the breakdown and formation of enzyme-substrate complexes rather than a simple ratio of these constants.

b. **Vmax/2**: This option is incorrect as KM specifically refers to substrate concentration, not the velocity directly.

c. **[S] at Vmax/2**: This is the correct representation. KM is defined as the substrate concentration ([S]) at which the reaction velocity is half of Vmax (maximum velocity).

Understanding KM helps in determining the affinity of an enzyme for its substrate; a lower KM indicates a higher affinity, meaning less substrate is needed to reach half of the maximum reaction rate.

Expert Solution

Step 1

Step by step

Solved in 2 steps with 2 images

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Quality Assurance and Calibration Methods

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

Pls answer thank u
Mganga is doing a routine analysis in a copper plating factory. He is regularly making up solutions of verypure CuSO4.5H2O. He suspect that a batch of a reagent used to make up a stock solution of CuSO4.5H2Ois impure and it may contains some CuCl2. He asked you to determine the percentage impurity as follows:Dissolve1.500g of a mixture and make up to 1.00L mark.150mL of this solution was treated with 20.00mLof 0.100M AgNO3 to remove 98.6% of chloride as AgCl precipitate.
integration for 7.24 ppm will be set to 4 5.16 ppm 7.34 ppm H. End group 4.36 ppm 5.10 ppm H На H3C H H3C HHa H. HO. H3C H H3C 4.86 ppm H. 5.16 ppm H 7.34 ppm Hp 144.13/2 xn H. На 144.13/2 x n DDL 170.2 x n DDDL 198.3 x n 138.2 n= integration area of that proton relative to H set to 4 hydrogens Explain why the L-lactide methine protons, H, in the polymer are observed downfield from the (do)decalactone methine protons, H,. b.
9
Explain both the parts with details. I will give thumbs up if explanation is satisfactory and solve as soon as possible
4. Ksp=4.1x10-36 for Pb3(AsO4)2Calculate Eofor Pb3(AsO4)2(s) + 6e-  3Pb(s) + 2AsO43-Pb2+ +2e-  Pb(s) Eo= -0.126 V
I need help rewriting this without copying word by word. Could you help me? Could you also use different references from different sources?
10. The 1/v axis of a reciprocal plot is labeled 10°. The 1/[S] axis is labeled [S]': (M)'x 10.) The plot intersects the two axes at "2" v: (nmoles × literx min')" and "-4," respectively. What are Vmax 66 and Km ?
How do you find the Ksp and solubility limit for SrSO4 given [Sr]=0.000583095 & [SO4]=0.000583095?
). Continued. 6- N 7. 8. 9. OH CN CN CHBLI BY 130: A 2 CH3Li 2 Hedi LAH1/H35: -mg Br H3 8: 2 Oliv roger H35 mgBry M33 рес, сH2Cl2 mg/ED₂D нсно, над PCC, CH₂Cl₂ CH3 mg Br он H₂3: -CHT
Give a clear handwritten answer with explanation ..
3. Consider a mixture of isobutene(1) + butane(2): CH, CH,CH,CH,CH, CH, = c- CH, (1) (2) a. Calculate the surface area and volume parameters for each molecule. Which component has a larger liquid molar volume and surface area? b. Calculate the volume fractions for an equimolar mixture.