The end-replication problem (telomere problem) exists in eukaryotic chromosomes and is characterized by the chromosomes shortening with each round of DNA replication. Select the statements that best explain why the end-replication problem exists in eukaryotic chromosomes. DNA polymerase synthesizes DNA from the 5' end to the 3' end. The lagging strand is synthesized from the hydroxyl end to the phosphate end. DNA ligase links the 5' OH group of one fragment to the 3' phosphate group of an adjacent fragment. DNA polymerase requires a primer for DNA synthesis. The RNA primer is removed in a 3' to 5' direction.

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Gene Interactions

When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.

Gene Expression

Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.