The end-replication problem (telomere problem) exists in eukaryotic chromosomes and is characterized by the chromosomes shortening with each round of DNA replication. Select the statements that best explain why the end-replication problem exists in eukaryotic chromosomes. DNA polymerase synthesizes DNA from the 5' end to the 3' end. The lagging strand is synthesized from the hydroxyl end to the phosphate end. DNA ligase links the 5' OH group of one fragment to the 3' phosphate group of an adjacent fragment. DNA polymerase requires a primer for DNA synthesis. The RNA primer is removed in a 3' to 5' direction.

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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The end-replication problem (telomere problem) exists in eukaryotic chromosomes and is characterized by the chromosomes
shortening with each round of DNA replication.
Select the statements that best explain why the end-replication problem exists in eukaryotic chromosomes.
DNA polymerase synthesizes DNA from the 5' end to the 3' end.
The lagging strand is synthesized from the hydroxyl end to the phosphate end.
DNA ligase links the 5' OH group of one fragment to the 3' phosphate group of an adjacent fragment.
DNA polymerase requires a primer for DNA synthesis.
The RNA primer is removed in a 3' to 5' direction.
Transcribed Image Text:The end-replication problem (telomere problem) exists in eukaryotic chromosomes and is characterized by the chromosomes shortening with each round of DNA replication. Select the statements that best explain why the end-replication problem exists in eukaryotic chromosomes. DNA polymerase synthesizes DNA from the 5' end to the 3' end. The lagging strand is synthesized from the hydroxyl end to the phosphate end. DNA ligase links the 5' OH group of one fragment to the 3' phosphate group of an adjacent fragment. DNA polymerase requires a primer for DNA synthesis. The RNA primer is removed in a 3' to 5' direction.
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