The desire steady state concentration of a drug is 5mg/l. Clearance of the drug is 30l/hr and its volume of distribution is 150l. a) What infusion rate will be necessary to reach the target concentration? b) How long will it take to reach steady state? c) What loading dose will be required to instantaneously achieve the steady state?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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The desire steady state concentration of a drug is 5mg/l. Clearance of the drug is 30l/hr and its volume of distribution is 150l.
a) What infusion rate will be necessary to reach the target concentration?
b) How long will it take to reach steady state?
c) What loading dose will be required to instantaneously achieve the steady state?

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