The data set attached presents the results of a testcross using female flies heterozygous for three traits and male flies, which are homozygous recessive. For simplicity, mutant alleles are shown with letters a, b, and c and wildtype alleles are indicated by a “+” symbol. For this part of the report do the following in order:
a) Determine the gene order (which gene is in the middle?)
d) Construct a genetic map for the three genes, including the map distances between them. Clearly indicate the logic you followed and show all your calculations. Include the full distance calculations for the two most distanced genes (do not just add the other 2 distances).
Ensure the work is neat and clear and does not contain spelling or grammatical errors so that it is understandable. Make sure to double check the solution provided.
Step by stepSolved in 4 steps with 2 images
- The miniature gene in Drosophila is located on the X-chromosome, It has two alleles: the mutant allele (m") encodes for wings that are reduced in size and is recessive to the wild-type (m*) allele that encodes for a normal size wing. What is the genotype of a true breeding, miniature male? of Select one: a. Xm /Y cross out O b. Xm+ /Y cross out O c. mt/m cross out O d. Xm+ Xm cross out e. Xm+/Xm cross out Of. X/X cross out g. m / m* cross out h. m/m cross outarrow_forwardThe diagram below represents results of agarose gel electrophoresis performed after PCR amplification of a molecular marker in diploid organisms. Answer the following questions: a) How many individuals are homozygous and how many are heterozygous? b) How many alleles are there in this population?arrow_forwardThe wild-type (normal) fruit fly, Drosophila melanogaster, has straight wings and long bristles. Mutant strains have been isolated with either curled wings or short bristles. The genes representing these two mutant traits are located on separate chromosomes. Carefully examine the data from the five crosses below. (a) For each mutation, determine whether it is dominant or recessive. In each case, identify which crosses support your answer; and (b) define gene symbols and determine the genotypes of the parents for each cross. Cross 1. straight, short X straight, short 2. straight, long X straight, long 3. curled, long X straight, short 4. straight, short X straight, short 5. curled, short X straight, short straight wings, long bristles 30 120 40 40 20 Number of Progeny straight curled wings, wings, short long bristles bristles 90 10 0 40 120 60 40 40 0 20 curled wings, short bristles 30 0 40 0 60arrow_forward
- In a three-point linkage analysis, the RF (Recombinant Frequency) for three genes were determined as the following: genes A and B (RF=15%), genes B and C (RF=22%), genes A and C (RF=35%). Based on this analysis, which one of three genes is located in the middle? O gene B Ogene A O gene C O cannot be determinedarrow_forwardIdentity gene 1 (bl, pr, vg) Identity gene 2 ( bl, pr, vg) Identity gene 3 ( bl,pr, vg) How many map units separate genes 1 and 2 ( Distance 1)? How many map units separate genes 2 and 3 ( distances 2) ?arrow_forwardPlease Explainarrow_forward
- Based on the data in Table 1, which individual(s) is/are heterozygous? Select all that apply a) B IV-8 b) C IV-3 c) B IV-9 d) A IV-3arrow_forwardplease explain why answer is C thoroughly with steps thank you :)))arrow_forwardGiven the experimental set up below, and knowing the genes for stalked eyes (st) and black bodies (b) are on the same chromosome and recessive to wild type (un-stalked eyes and light body). F2= a=489, b=56, c=497, d=49 A) How many recombinant animals are in the F2 generation? B) ( How far apart, (as both a % recombination and in map units) are the stalk eyed and black bodied genes on this chromosome?arrow_forward
- In c. elegans, genetics model organism, movement problems (unc) and small body size (sma) are encoded by two mutant alleles that are recessive to those that produce wild-type traits (unc+ and sma+). A worm homozygous for movement problems and small body is crossed with a worm homozygous for the wild-type traits. The F1 have normal movement and normal body size. The F1 are then crossed with worms that have movement problems and small body size in a testcross. The progeny of this testcross is: Normal movement, normal body size 210 Movement problems, normal body size 9 Normal movement, small body size 11 Movement problems, small body size 193 a)From the test cross results, can you tell if the two genes are on the same chromosome or not? Explain your reasoning. b)What phenotypic proportions would be expected if the genes for round eyes and white body were located on different chromosomes? (please explain hot to get to these conclusions)arrow_forwardShown here is PCR-based analysis of mouse pups from an experiment designed to evaluate the phenotypic impact of the sex-reversed Y chromosome gene (SRY). Interpret the data shown here clearly, defining the importance of each mouse tested and interpreting the results. Which mouse (of the three shown) is likely transgenic for Sry? Explain.arrow_forwardBelow is a pedigree showing transmission of a disease; affected individuals are indicated by solid circles or boxes. Represented below the pedigree are two nylon membranes; DNA samples from each individual in the pedigree were spotted in identical fashion on each membrane. Each individual's DNA appears directly below his or her position in the pedigree. Each membrane was hybridized with allele specific oligonucleotides that detect the two alternative alleles of a single SNP locus (ASO 1 and ASO 2). Positive hybridization is represented as a filled circle and lack of hybridization is represented as an open circle. I 11 III IV V ASO 1 ASO 2 To 1 2 3 4 5 6 a. What is the mode of transmission of this disease? 12 b. Which SNP allele (ASO1 or ASO2) is originally linked to the disease gene? c. Draw a diagram of the event that gave rise to the genotype of individual IV-5. d. Individual V-1 is an unborn fetus. If the SNP locus is 10 CM from the disease locus, what is the likelihood that he will…arrow_forward
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education