the chemical group responsible for nucleophilic attack in translational elongation is  a) free alpha-NH2 group on amino acid of A site aminocyal tRNA b) the 3=hydroxyl on the 3' end ribose c) the oxygen on the alpha phosphate of the incoming NTP d) the 5= hydroxyl on the 5' end deoxyribose e) an oxyanion on the Y-phosphate of the dNTP

the difference in primary structure between related tropomyosin informs arises from a) alternative splicing b) C-to-U editing  c) farnesylation d) H3K4 methylation e) targetting to secretory vesicles

Why do aminoacyl-tRNA synthetases need ATP? to prevent the 2'OH from being aminoacylated to provide energy to drive the reaction to add the 3' adenosine onto the tRNA to add a leaving group on the amino acid

What enzyme catalyzes protein synthesis in bacteria? You discover a new broad-spectrum antibiotic that inhibits protein synthesis and named it Compound J. You want to determine the mechanism of action of Compound J. After treating bacteria cells with Compound J, you observe many ribosomes with long polypeptide chains bound to them. Based on this observation, make a hypothesis about which part of the ribosome Compound J is binding and how this specifically affects translation. What evidence supports that proper protein folding is essential to all domains of life? Name and describe the function/s of two specific molecules that help proteins fold in bacteria.

Posttranslational modifications of proteins do not include: peptide bond formation glycosylation acetylation of N-terminal peptide bond cleavage disulfide bond formation QUESTION 16 14 15 16 streptomycin puromycin 17 18 19 20 Which one of the following antibiotics does NOT function by interfering with the translational/post-translation process tunicamycin penicillin O tetracyclin O O

Given the following diagram of how protein AWESOME1 binds to it's target DNA, describe the potential effects of each of the 5 mutations shown below. The wild-type sequence of a helix #1 is also shown in the blue box, and all the mutations are in helix #1 (see numbers for identifying particular residues). a helix #1 R(1)-V-I-L-Y-F-W-I-M-Y-F-S-H-Y-W-R(16) #1 Predict the consequence of the following mutations: 1) Arg(1) to Glu 2) Arg(1) to Ala 3) Phe(6) to lle 4) Trp(7) to Phe 5) Met(9) to Pro in