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Genetic Variation
Genetic variation refers to the variation in the genome sequences between individual organisms of a species. Individual differences or population differences can both be referred to as genetic variations. It is primarily caused by mutation, but other factors such as genetic drift and sexual reproduction also play a major role.
Quantitative Genetics
Quantitative genetics is the part of genetics that deals with the continuous trait, where the expression of various genes influences the phenotypes. Thus genes are expressed together to produce a trait with continuous variability. This is unlike the classical traits or qualitative traits, where each trait is controlled by the expression of a single or very few genes to produce a discontinuous variation.
The "balance" theory by Dobzhansky
-is a theory based on the idea that genetic diversity in a population is maintained by heterozygote superiority. |
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-is a theory that predicts a low level of genetic diversity in a given population. |
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-was proposed in contrast to the so-called "classical" theory which hypothesized that individuals in a given diploid population should mostly be carrying neutral mutations in their genomes. |
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-has been confirmed by numerous modern-day population genetic surveys, demonstrating the important of neutral mutations and genetic drift. |
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-All of the above |
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Solved in 2 steps
- The eugenic movement was created in the early 20th century by Sir Francis Galton. Its aim was to improve the genetic pool of the human population by selective breeding. One idea was to discourage individuals with Mendelian autosomal recessive diseases to have children. However, the fallacy of this idea is shown by the fact that recessive lethal alleles (that are never found in homozygosity) can persist in populations for hundreds to thousands of generations. Which one of the following statements best explains the persistence of those alleles in populations? There is heterozygote advantage in those populations. Recessive alleles keep being produced by mutation. Recessive alleles cannot be selected against when present in heterozygotes. Genetic drift keeps recessive alleles at a relative high frequency in populations. Consider the action of mutation and of genetic drift in a population. What do you expect genetic variation will be in a…You are studying an autosome trait. There are two alleles, one showing complete dominance over the other. In a population, 84% of the individuals show the dominant phenotype. Assuming that this population is under Hardy-Weinberg equilibrium, which of the following statement is TRUE? 36% of individuals have the homozygous dominant genotype. 40% of the alleles in the population is recessive. 16% of the alleles in the population is recessive. 60% of individuals have the dominant alleles.A hypothetical ancestral population (AABB) splits into two independent lineages. Mutations produce different new alleles fixed at each loci in each population (AAbb in one population, aaBb in the other). According to the Dobzhansky-Muller model, which genotype would not be viable if the F1 individuals were inviable? O aabb Aabb aaBB AABB AABb
- What is the role of variation in evolution.if heterozygosity is reduced, what happens to the potential for evolution. The phenotype and genotyoe of a population is due to a mosaic of random and directed processes. Some of these have to do with history , discuss the role of chance and directions in evolution and in determining the phenotype of a population.In sexually reproducing species, each individual begins life with DNA inherited from both parent organisms. , Apply this idea to what occurs when organisms of two species that have homologous chromosomes mate and produce ( F1 ) hybrid offspring. What percentage of the DNA in the F1 hybrids' chromosomes comes from each parent species? As the hybrids mate and produce F2 and later-generation hybrid offspring, describe how recombination and natural selection may affect whether the DNA in hybrid chromosomes is derived from one parent species or the other.In Africa we find albinism in around 1 in every 5,000 individuals. This is puzzling, because albinism may reduce survival, for instance due to increased risk of skin cancer. What evolutionary mechanism (natural selection, mutation, genetic drift, or gene flow) is a viable explanation for the consistent observation of a few children born with albinism each generation and why?
- Calculate the probability a new mutation, with one copy in the population, is lost by random genetic drift in the next generation for the following diploid populations: [a] N=5 [b] N=25 [c] N=1250A beneficial dominant mutation is expected to take fewer generations to reach high frequency than a beneficial recessive mutation at the same locus in the same population, assuming neither mutation is lost to genetic drift. True False Which of the following statements is true of recombination? Recombination reshuffles alleles between maternal and paternal chromosomes, but not does produce new alleles. Recombination can produce new alleles by crossing over between maternal and paternal chromosomes. Recombination is more likely between loci that are near each other on a chromosome. Recombination occurring between loci on non-homologous chromosomes results in linkage equilibrium. Recombination occurring between loci on non-homologous chromosomes results in linkage disequilibrium.Applying the Hardy-Weinberg equilibrium. In a population of flowers, the following color distribution was noted: 36% red (RR), 48% brown-red (Rr), and 16% fuschia (rr). What will be the distribution of genotypes in the next generation?
- Which of the following best describes a pair of homologous chromosomes? a- A pair of chromosomes that have the same alleles of the same genes arranged in the same order b- A pair of chromosomes that have the same genes, but arranged in a different order, and with potentially different alleles of some of the genes c- A pair of chromosomes that have different alleles of the same genes arranged in different order d- A pair of chromosomes that have the same genes in the same order, but possibly with different alleles of some of the genesFor the trichome selection experiment, the null hypothesis is that there will be no difference between the mean number of trichomes in the second generation compared to the parent generation. The following bar graph shows the data from the experiment, including error bars showing ± 2 standard deviations (a measure of variation for a group of data as a whole). Based on the data provided, do you reject or fail to reject the null hypothesis? Select the answer that most strongly supports your choice and correctly justifies the response. Based on the data provided, do you reject or fail to reject the null hypothesis? Select the answer that most strongly supports your choice and correctly justifies the response. A. Reject the null hypothesis, as variation, shown by the error bars, is greater after selection. B. Reject the null hypothesis, as there is no overlap between the means as shown by the error bars. C. Reject the null hypothesis, as the error bars for the two groups show…Remember that understanding is explanations more than facts. Definitions of phenotype, genotype, allele, gene, microevolution, macroevolution Know that in humans, most of the genetic variation is observed within populations, and know why that is. Know the 4 processes of evolution (3 neutral + natural selection) Know that evolution isn't progressive and doesn't necessarily lead to more complexity Know that evolution can lead to traits that decrease survival (ex: sexual selection) Know that quantitative traits are generally influenced by (i) many genes, each having a small effect on the trait value; and (ii) the environment What is F1 like when you cross 2 homozygotic lines of peas of different colors? What is F2 like when you cross F1 individuals (remember what 9:3:3:1 is about) Know what genetic dominance is about Definitions of chromosome, nucleus, mitosis, meiosis, crossing over How many chromosomes in humans? How many pairs of chromosomes? Know and apply Hardy-Weinberg's equation…