The African swine fever virus has two membrane bilayers around the outside of the virus. The outer layer is from the host cell that the virus infects—it takes part of the host membrane with it as it leaves the cell. This membrane then fuses with the next cell the virus infects, and it is known that cholesterol is required in the membrane of the cell being infected in order for the virus to successfully infect the cell. Which of the following is the best explanation for why cholesterol would be required in the membrane of the cell the virus is infecting? Explain your choice in 25 words or less.Viral proteins may not have the correct conformation if the host membrane is less fluid due to lower cholesterol levelsThe cholesterol forms a channel through the membrane that allows the virus to enter the cell, and without cholesterol the virus cannot enter the cellThe cholesterol disrupts a small portion of the hydrophobic core of the membrane to allow the virus to enter the cell, and without cholesterol the virus cannot enter the cellNone of the above answers is a good explanation for why cholesterol is required in the membrane of the infected cell

Cholesterol forms a component in the cell membrane of the cell. And it is required for the African…

Answered: The African swine fever virus has two…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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The African swine fever virus has two membrane bilayers around the outside of the virus. The outer layer is from the host cell that the virus infects—it takes part of the host membrane with it as it leaves the cell. This membrane then fuses with the next cell the virus infects, and it is known that cholesterol is required in the membrane of the cell being infected in order for the virus to successfully infect the cell. Which of the following is the best explanation for why cholesterol would be required in the membrane of the cell the virus is infecting? Explain your choice in 25 words or less.
1. Viral proteins may not have the correct conformation if the host membrane is less fluid due to lower cholesterol levels
2. The cholesterol forms a channel through the membrane that allows the virus to enter the cell, and without cholesterol the virus cannot enter the cell
3. The cholesterol disrupts a small portion of the hydrophobic core of the membrane to allow the virus to enter the cell, and without cholesterol the virus cannot enter the cell
4. None of the above answers is a good explanation for why cholesterol is required in the membrane of the infected cell

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