technique called “GCMS” is often used instead of simple GC analysis. This technique entails passing a sample through a gas chromatography instrument and replacing the standard GC detector with a mass spectrometer (the “MS” part). What advantages do you think GCMS has over GC as well as simple MS?

In an experiment of Reverse Phase chromatography using C-18 stationary phase and a mixture of methanol/ethyl acetate/acetic acid, a researcher tried to separate the 3 compounds shown below. Which compound would have the lowest Rf and which the highest Rf in this experiment? Explain your answer and show any relevant structures.

QUESTION T5 Why were the areas underneath the peaks in the gan chromatographs you eobtained mutiplied by a weight tactor? DA the corrction factor compensates for user error OB Rame lonization detectors (FID) respond slightly dfferent to compounds with diferent molecular weights OCnone of the answers OD. the GC (GOW MAC 350) used contains a quadrapole mass spec detector whose response must be corrected for the miz ratio of the diferent ions obtainen for diferert moleculestune OE not all molecules have the same themmal conductivity QUESTION 16 Which list of functional groups is present in the anti-viral drug Arbidol HO Br O A Thioether, alkene, ester, amide, amine O 8. Thioether alcohol, ester, amine OC Alcohol, ether, amide, epoxide, thioester OD. Ether, ketone olefin, amine, alcohol O E Thioalcohol, alkene, ether, amine, nitro

Give at least two reasons for using very dilute solutions when doing fluorescence spectrometry