Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Environmental health and hazards
An organism's environment is the environment in which it lives and has an impact on its well-being. The World Health Organization (WHO) defines environmental health as "those aspects of public health, such as quality of life, that are influenced by physi…
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Question 17 Individuals with Beckwith-Wiedemann syndrome (BWWS) develop sporadic tumors due to a mutation in an imprintable gene, p57, on chromosome 11. Normally, p57 regulates the cell cycle. The imprint on p57 is such that only the maternal allele is expressed. A heterozygous normal couple has two children with BWS and one normal child. How is it possible that both parents have the mutant p57 allele to pass along, but these parents do not themselves show the cancerous phenotype? A) Each must have received the mutant p57 allele from their respective fathers. B) Each must have received the mutant p57 allele from their respective mothers. C) The mother must have received the mutant p57 allele from her mother, while the father must have received the mutant p57 allele from his father. D) The mother must have received the mutant p57 allele from her father, while the father must have received the mutant p57 allele from his mother. E) Actually, there's something inconsistent here. Such phenotypes for the parents are not anticipated when an imprintable gene is involved. CS Scanned with CamScanner
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Transcribed Image Text:Question 17 Individuals with Beckwith-Wiedemann syndrome (BWWS) develop sporadic tumors due to a mutation in an imprintable gene, p57, on chromosome 11. Normally, p57 regulates the cell cycle. The imprint on p57 is such that only the maternal allele is expressed. A heterozygous normal couple has two children with BWS and one normal child. How is it possible that both parents have the mutant p57 allele to pass along, but these parents do not themselves show the cancerous phenotype? A) Each must have received the mutant p57 allele from their respective fathers. B) Each must have received the mutant p57 allele from their respective mothers. C) The mother must have received the mutant p57 allele from her mother, while the father must have received the mutant p57 allele from his father. D) The mother must have received the mutant p57 allele from her father, while the father must have received the mutant p57 allele from his mother. E) Actually, there's something inconsistent here. Such phenotypes for the parents are not anticipated when an imprintable gene is involved. CS Scanned with CamScanner
Question 10 Consider that a certain gene is a maternal effect gene and that the allele for dark brown pigment is incompletely dominant to the allele for no pigment (white). The incomplete dominant phenotype is light tan. If a white female is crossed with dark brown male, what will be the phenotypic ratio of the progeny? A) all white B) all dark brown C) all light tan D) either all white or all light tan E) 'either all light tan or all dark brown F) none of the above choices (cannot be determined) CS Scanned with CamScanner
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Transcribed Image Text:Question 10 Consider that a certain gene is a maternal effect gene and that the allele for dark brown pigment is incompletely dominant to the allele for no pigment (white). The incomplete dominant phenotype is light tan. If a white female is crossed with dark brown male, what will be the phenotypic ratio of the progeny? A) all white B) all dark brown C) all light tan D) either all white or all light tan E) 'either all light tan or all dark brown F) none of the above choices (cannot be determined) CS Scanned with CamScanner
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