Surgery and germs. Joseph Lister (for whom Listerine
is named!) was a British physician who was interested
in the role of bacteria in human infections. He suspected
that germs were involved in transmitting infection, so he
tried using carbolic acid as an operating room disinfectant.
In 75 amputations, he used carbolic acid 40 times. Of the
40 amputations using carbolic acid, 34 of the patients
lived. Of the 35 amputations without carbolic acid,
19 patients lived. The question of interest is whether
carbolic acid is effective in increasing the chances of
surviving an amputation.
a) What kind of a study is this?
b) What do you conclude? Support your conclusion by
testing an appropriate hypothesis.
c) What reservations do you have about the design of
the study?
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