Suppose in a hospital in the United Kingdom, out of 98,543 of babies born in the last 20 years, 13 children were born with myotonic dystrophy. Myotonic dystrophy is caused by an autosomal dominant mutation in the dystrophia myotonica protein kinase gene, DMPK. Myotonic dystrophy causes progressive muscle weakness, cataracts, and difficulty relaxing clenched hands. Of the 13 affected children, only 3 were born to a parent with a DMPK mutation. Given this information, what is the mutation rate of the DMPK gene?

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Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.