Starting Compound Typical Reagents Compound Class and Reaction Class Conditions Formed OH R' :Nu R- ral or Ероxide basic Nu Alcohol (2-substituted) OH R' R' H-Nu R

Chemistry
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Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Chapter1: Chemical Foundations
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What is the mechanisms to get from the reactant to the products
**Functional Group Transformations**

| Starting Compound Class | Typical Reagents and Reaction Conditions | Compound Class Formed |
|-------------------------|------------------------------------------|-----------------------|

**(10)**
- **Starting Compound Class:** Epoxide
- **Typical Reagents and Reaction Conditions:** Neutral or basic conditions with a nucleophile (\( \text{Nu}^- \))
- **Compound Class Formed:** Alcohol (2-substituted)

Diagram:
- The epoxide structure is attacked by a nucleophile, resulting in a ring-opening reaction. This forms an alcohol with a new substituent at the 2-position where the nucleophile added.

**(11)**
- **Starting Compound Class:** Epoxide
- **Typical Reagents and Reaction Conditions:** Acidic conditions with a nucleophile (\( \text{H-Nu} \))
- **Compound Class Formed:** Alcohol (2-substituted)

Diagram:
- Under acidic conditions, the epoxide undergoes a ring-opening reaction involving a nucleophile. The resulting product is a 2-substituted alcohol, similar to the neutral/basic reaction but typically with different regioselectivity.
Transcribed Image Text:**Functional Group Transformations** | Starting Compound Class | Typical Reagents and Reaction Conditions | Compound Class Formed | |-------------------------|------------------------------------------|-----------------------| **(10)** - **Starting Compound Class:** Epoxide - **Typical Reagents and Reaction Conditions:** Neutral or basic conditions with a nucleophile (\( \text{Nu}^- \)) - **Compound Class Formed:** Alcohol (2-substituted) Diagram: - The epoxide structure is attacked by a nucleophile, resulting in a ring-opening reaction. This forms an alcohol with a new substituent at the 2-position where the nucleophile added. **(11)** - **Starting Compound Class:** Epoxide - **Typical Reagents and Reaction Conditions:** Acidic conditions with a nucleophile (\( \text{H-Nu} \)) - **Compound Class Formed:** Alcohol (2-substituted) Diagram: - Under acidic conditions, the epoxide undergoes a ring-opening reaction involving a nucleophile. The resulting product is a 2-substituted alcohol, similar to the neutral/basic reaction but typically with different regioselectivity.
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