Show how you would synthesize the following compounds from alkyl halides, vinylhalides, and aryl halides containing no more than six carbon atoms. trans-oct-3-ene
Show how you would synthesize the following compounds from
halides, and aryl halides containing no more than six carbon atoms.
trans-oct-3-ene
A Corey-House alkene synthesis reaction is the reaction of the alkene. In this reaction lithium diorganyl cuprate (R2CuLi) with an organyl (pseudo)halide (R'X). Vinyl lithium compound is used to form an alkene. Copper iodide is used as the catalyst. Vinyl part of reactant generally attached to form vinyl lithium cuprate.
Reaction:
To synthesize trans-oct-3-ene (E isomer resembles trans-isomer), Reaction used is called Corey-House alkene synthesis reaction. (E)-pent-2-en-1-yllithium is used to react with copper iodide, to form dialkyl lithium cuprate. This reaction is followed by the addition of 1-bromopropane. This will give trans-oct-3-ene.
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