Referring to the graph, what phases together would account for approximately 25% of the time spent from a cell in the cell cycle? A) M phase and S phase B) S phase and M phase C) G1 phase and M phase D) G2 phase and M phase

Progression of cells through the division cycle is regulated by both extracellular (environmental) and internal signals that monitor and coordinate processes during phases of cycle. a) True b) False

What statement about Cdks/Cyclins below is false? A) Cyclins phosphorylate Cdks B) Cdks are kinases C) Cdk expression is constant during the cell cycle D) Cyclin expression fluctuates during the cell cycle E) Cdk activity fluctuates during the cell cycle

Cyclin B and Cdk1 make up MPF which is important to the regulation and initiation of mitosis. : a) True b) False

The stages of the cell cycle, are in part, regulated by A) sister chromatids B) G2 C) ploidy D) cyclin concentrations

Referring to the graph, what phases together would account for approximately 25% of the time spent from a cell in the cell cycle?A) M phase and S phaseB) S phase and M phaseC) G1 phase and M phaseD) G2 phase and M phase

One approach to studying the regulation of cell cycle progression (particularly in an era when genetic and molecular biology manipulations were less readily accomplished in mammalian cells) was to use treatments that induced cells to fuse and then monitor the behavior of the two nuclei in the resulting cell. The figure below depicts data from one such study.  The investigators did preliminary work to produce populations of cells that were synchronized in various stages of the cell cycle (G1, S, or G2 in the examples shown below). They then fused the cells in different combinations and monitored subsequent events in each of the nuclei. For purposes of this question, we will pay particular attention to what occurred in the nucleus that came from the cell in G1. In one experiment (I), cells in the G1 and S phases were fused.  That event caused the nucleus from the G1 cell to very quickly enter the S phase (sooner than it would otherwise have done so).  In contrast, in a second experiment…

What are the three types of microtubules involved in the formation of the mitotic spindle? Briefly describe the contribution of each to successful cell division.

If the most basic function of the cell cycle is to accurately duplicate the DNA in the chromosomes and distribute the copies precisely to the daughter cells, why are there gaps between S-phase and M-phase?

14) The plus-end of the microtubule (select all that apply) a) has the same structure as the minus-end b) connect to kinetochores in the mitotic spindle c) connect to centrosomes in the mitotic spindle d) have proteins that bind and change plus-end dynamics e) None of the above