Quite often, medications cannot be taken with grapefruit juice. This is because grapefruit juice blocks an enzyme responsible for metabolism of the drug. Chemicals ingrapefruit juice bind to the active site of the enzyme. What type of inhibition is this, and what would it do to the amount of medication in your blood? Why is this bad for you explain?

Fluconazole is used to treat yeast infections by inhibiting the production of ergosterol. What would happen if you took away the ability for the yeast to produce ergosterol?

The effectiveness of allosteric effectors in regulating metabolic pathways is based on their ability to—     interact with multiple substrate-binding sites on the target enzyme(s).     interfere with competitive inhibitors.     alter the concentration of the target enzyme(s).     denature the target enzyme(s).     change the conformation of the target enzyme(s).

Proteases are one of the main drug targets. Choose the False statement regarding proteases. A. Proteases are enzymes that cleave peptide bonds. B. Water is a reactant in the reaction catalyzed by proteases. C. Proteases, like all enzymes show substrate specificity, meaning they cleave only substate that fit the bonding product. D. Proteases rely on the proton transfer from NADH to the substrate. E. Protease mechanism involves only acid-base catalysis.