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QUESTION 8 Which of the following is true of the RAS proto-oncogene? O Mutations involving RAS are dominant in their effects. O Cancer cells typically show both alleles have loss of function mutations. OA gain of function mutation in just one allele would signal to the cell to proceed through the cell cycle. O A gain of function mutation in one allele would be hidden or masked by the presence of a normal, wild-type allele. O Deletion of both alleles would signal to the cell to proceed through the cell cycle. QUESTION 9 Which of the following is true regarding tumor suppressor genes? O Knudson's two-hit mutation model applies to these genes. O Typical cancer cells show gain of function of tumor suppressors. O Typical cancer cells show inactivating, loss of function mutation in these genes. O Tumor suppressor mutations are recessive in their effects on the cell.

QUESTION 8 Which of the following is true of the RAS proto-oncogene? O Mutations involving RAS are dominant in their effects. O Cancer cells typically show both alleles have loss of function mutations. OA gain of function mutation in just one allele would signal to the cell to proceed through the cell cycle. O A gain of function mutation in one allele would be hidden or masked by the presence of a normal, wild-type allele. O Deletion of both alleles would signal to the cell to proceed through the cell cycle. QUESTION 9 Which of the following is true regarding tumor suppressor genes? O Knudson's two-hit mutation model applies to these genes. O Typical cancer cells show gain of function of tumor suppressors. O Typical cancer cells show inactivating, loss of function mutation in these genes. O Tumor suppressor mutations are recessive in their effects on the cell.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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QUESTION 8 Which of the following is true of the RAS proto-onoogene? O Mutations involving RAS are dominant in their effects. O Cancer cells typically show both alleles have loss of function mutations. OA gain of function mutation in just one allele would signal to the cell to proceed through the cell cycle. O A gain of function mutation in one allele would be hidden or masked by the presence of a normal, wild-type allele. Deletion of both alleles would signal to the cell to proceed through the cell cycle. QUESTION 9 Which of the following is true regarding tumor suppressor genes? O Knudson's two-hit i model applies to these genes. Typical cancer cells show gain of function of tumor suppressors. O Typical cancer cells show inactivating, loss of function mutation in these genes. Tumor suppressor mutations are recessive in their effects on the cell.
Transcribed Image Text:QUESTION 8 Which of the following is true of the RAS proto-onoogene? O Mutations involving RAS are dominant in their effects. O Cancer cells typically show both alleles have loss of function mutations. OA gain of function mutation in just one allele would signal to the cell to proceed through the cell cycle. O A gain of function mutation in one allele would be hidden or masked by the presence of a normal, wild-type allele. Deletion of both alleles would signal to the cell to proceed through the cell cycle. QUESTION 9 Which of the following is true regarding tumor suppressor genes? O Knudson's two-hit i model applies to these genes. Typical cancer cells show gain of function of tumor suppressors. O Typical cancer cells show inactivating, loss of function mutation in these genes. Tumor suppressor mutations are recessive in their effects on the cell.
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