Question 14 vytorin is a drug that combines ezetimibe and simvastatin, which block both cholesterol uptake from the gastrointestinal tract and cholesterol synthesis by all cells. A confused individual accidently takes an overdose of Vytorin. After a week, she is severely hypocholesterolemic (l.e., has very low levels of circulating cholesterol). Which hormone would be present at a lower level than normal? A. Calcitriol OB. Leptin OC. Gonadotropin releasing hormone OD. Cortisol O E. Follicle stimulating hormone

Question 24 Which of the following is an effect of epinephrine? OA. Enhanced pain sensation B. Slowed heart rate OC. Increased GLUT4 cell surface expression in skeletal muscle D. Increased blood flow to the Gl E. Increase liver gluconeogenesis

QUESTION 13 There is a sleep-promoting factor that accumulates throughout the days as a by-product of cellular metabolism. What is its name and where does it act?   A. Orexin acting in the tuberomammillary nucleus (TMN )   B. Acetylcholine acting in the pontine reticular formation.   C. Orexin acting in the ventrolateral preoptic nucleus (VLPO)   D. Adenosine acting in the ventrolateral preoptic nucleus (VLPO)   E. Nordrenaline acting in the suprachiasmatic nucleus   F. None of the above

QUESTION 1 Insulin can have pleiotropic (wide ranging) effects in cells because • The Insulin receptor phosphorylates a family of substrates inside cells. • There are over 20 versions of the Insulin receptor expressed in vertebrates. • The Insulin receptor heterodimerizes with the GH and PRL receptors. • MRAP (membrane associated receptor proteins) couple the Insulin receptor to different effector pathways inside cells. QUESTION 2 Cholecystokinin (CCK) is accurately described by which of the following statements? • It is not a member of a peptide hormone superfamily. • It binds to a 1 TMS receptor that signals through guanylate cyclase. • It is sulphated on tyrosine residues for full activity. • It is proteolytically released from POMC by gut cells. QUESTION 3 Insulin ... • is released from the pancreas in vertebrates and invertebrates. • Is released from the vertebrate pancreas in response to hyperglycemia. • is released from the vertebrate pancreas in a response to hypoglycemia. •…

Question 15 Which of the following is a consequence of glucocorticoid treatment for an extended period? O A. Reduced response to glucagon O B. Reduced response to ACTH C. Reduced IGF-1 synthesis O D. Inability to secret thyroid hormone O E. Hypoglycemia (low blood glucose)

Question 34 The following are events in the transmission of a signal at a chemical synapse. 1. Neurotransmitter binds with receptors associated with the postsynaptic membrane. Calcium ions rush into neuron's cytoplasm. 2. An action potential depolarizes the membrane of the presynaptic axon terminal. 3. The ligand-gated ion channels open. 4. The synaptic vesicles release neurotransmitter into the synaptic cleft. Which sequence of events is correct? O 3 2-5-1-4 0 1 2 3 4 5 O 3 2 5 4 1 04-3 1-2-5 Question 35 1 pts 1 pts

Question 32 Gluconeogenesis O creates glucose from FAT and protein O creates new leukocytes from cells other than the bone marrow O boosts your immunity lowers blood glucose similar to insulin

Question 35 Estrogens are found at lower levels in adult males than females, however, they are important in males for which of the following? O A. Sebum production OB. Sperm production O C. Muscle protein catabolism O D. Adipose lipid catabolism O E. As a dihydrotestosterone prohormone 1

Question 9 The product of the oxidation of glyceraldehyde 3-phosphate is: O 2-phosphoglycerate O 1,3-biphosphoglycerate O phosphoenolpyruvate O fructose 1,6-biphosphate oxaloacetate Previc

Question 31 Growth hormone stimulates adipose lipid catabolism by increasing transcription of the gene for which protein? A. GLUT2 O B. Tyrosine kinase OC. Protein kinase C O D. Phospholipase CB OE. Hormone sensitive lipase