
Organic Chemistry
8th Edition
ISBN: 9781305580350
Author: William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher: Cengage Learning
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Transcribed Image Text:Proteins are composed of long chains of amino acids linked together through amide bonds. In
the body, protease enzymes break down proteins into the individual amino acids by hydrolyzing the amide
bonds. Propose a plausible curved arrow mechanism for the hydrolysis of the dipeptide shown below
into the amino acids glycine and alanine under acidic conditions.
H20
H+
HO
H2N.
H2N
H2N
+
HO,
dipeptide
glycine
alanine
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