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Propose an efficient synthesis for the following transformation: The transformation above can be performed with some reagent or combination of the reagents listed below. Give the necessary reagent(s) in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution, provide just one answer. A в D t-BUOK 1) MeMgBr; 2) H3O* NazCr207, H2SO4. H2O NaOH E F G H H2, Lindlar's cat. 1) O3; 2) DMS TSCI, py dilute H2SO4 K L 1) LIAIH4: 2) HaО* DMP or PCC 1) EtMgBr; 2) H3o+ 1) ВHз-THF; 2) H202, NaOH

Propose an efficient synthesis for the following transformation: The transformation above can be performed with some reagent or combination of the reagents listed below. Give the necessary reagent(s) in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution, provide just one answer. A в D t-BUOK 1) MeMgBr; 2) H3O* NazCr207, H2SO4. H2O NaOH E F G H H2, Lindlar's cat. 1) O3; 2) DMS TSCI, py dilute H2SO4 K L 1) LIAIH4: 2) HaО* DMP or PCC 1) EtMgBr; 2) H3o+ 1) ВHз-THF; 2) H202, NaOH

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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**Synthesis Pathway Proposal for Organic Transformation:** **Objective:** Identify the appropriate sequence of reagents to convert the starting organic compound (3-chloropropane) into the target alcohol (butan-2-one). **Substrate and Product:** - **Starting Material:** A chlorinated hydrocarbon. - **Target Molecule:** A ketone. **Instructions:** Select the correct reagents from the list below to achieve the transformation. Write the chosen reagents as a string of letters (e.g., "EBF") without spaces or punctuation. **Reagents List:** **A**: t-BuOK **B**: 1) MeMgBr; 2) H₃O⁺ **C**: Na₂Cr₂O₇, H₂SO₄, H₂O **D**: NaOH **E**: H₂, Lindlar's cat. **F**: 1) O₃; 2) DMS **G**: TsCl, py **H**: dilute H₂SO₄ **I**: 1) LiAlH₄; 2) H₃O⁺ **J**: DMP or PCC **K**: 1) EtMgBr; 2) H₃O⁺ **L**: 1) BH₃∙THF; 2) H₂O₂, NaOH **Answer:** Enter the sequence of letters corresponding to the reagents that correctly transform the starting material to the final product in the provided box.
Transcribed Image Text:**Synthesis Pathway Proposal for Organic Transformation:** **Objective:** Identify the appropriate sequence of reagents to convert the starting organic compound (3-chloropropane) into the target alcohol (butan-2-one). **Substrate and Product:** - **Starting Material:** A chlorinated hydrocarbon. - **Target Molecule:** A ketone. **Instructions:** Select the correct reagents from the list below to achieve the transformation. Write the chosen reagents as a string of letters (e.g., "EBF") without spaces or punctuation. **Reagents List:** **A**: t-BuOK **B**: 1) MeMgBr; 2) H₃O⁺ **C**: Na₂Cr₂O₇, H₂SO₄, H₂O **D**: NaOH **E**: H₂, Lindlar's cat. **F**: 1) O₃; 2) DMS **G**: TsCl, py **H**: dilute H₂SO₄ **I**: 1) LiAlH₄; 2) H₃O⁺ **J**: DMP or PCC **K**: 1) EtMgBr; 2) H₃O⁺ **L**: 1) BH₃∙THF; 2) H₂O₂, NaOH **Answer:** Enter the sequence of letters corresponding to the reagents that correctly transform the starting material to the final product in the provided box.
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