Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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**Problem 5:** Suppose a cell expresses HK-I and 5 mM is the concentration of glucose in the blood. Compare the cellular concentration of glucose (relative to 5 mM) based on the G6P concentration in the cell being low or high.
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Transcribed Image Text:**Problem 5:** Suppose a cell expresses HK-I and 5 mM is the concentration of glucose in the blood. Compare the cellular concentration of glucose (relative to 5 mM) based on the G6P concentration in the cell being low or high.
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HK-1 is a type of hexokinase encoded by the HK1  gene. This enzyme produces glucose-6-phosphate by phosphorylating glucose. It can phosphorylate other hexoses too. Conversion of glucose to glucose-6-phosphate initiates the process of glycolysis which is associated with the production of energy-yielding molecules. Hexokinase is present on the mitochondrial outer membrane.

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