Predict the order of elution of a mixture of the following compounds from a column? Briefly explain. HO.

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**Question:** Predict the order of elution of a mixture of the following compounds from a column? Briefly explain.

**Compounds:**

1. **Biphenyl:** A structure consisting of two connected benzene rings.
2. **Benzoic Acid:** A benzene ring with a carboxylic acid group (COOH) attached.
3. **Ethyl Benzoate:** A benzene ring with an ester group (COOCH2CH3) attached.

**Analysis:**

In column chromatography, compounds are separated based on their polarity and interaction with the stationary phase. Non-polar compounds typically elute first as they interact less with the polar stationary phase, while polar compounds elute later due to stronger interactions.

**Order of Elution:**

1. **Biphenyl:** This compound is non-polar and will elute first.
2. **Ethyl Benzoate:** An ester, less polar than the acid, will elute second.
3. **Benzoic Acid:** Being the most polar due to the carboxylic acid group, it will elute last.
Transcribed Image Text:**Question:** Predict the order of elution of a mixture of the following compounds from a column? Briefly explain. **Compounds:** 1. **Biphenyl:** A structure consisting of two connected benzene rings. 2. **Benzoic Acid:** A benzene ring with a carboxylic acid group (COOH) attached. 3. **Ethyl Benzoate:** A benzene ring with an ester group (COOCH2CH3) attached. **Analysis:** In column chromatography, compounds are separated based on their polarity and interaction with the stationary phase. Non-polar compounds typically elute first as they interact less with the polar stationary phase, while polar compounds elute later due to stronger interactions. **Order of Elution:** 1. **Biphenyl:** This compound is non-polar and will elute first. 2. **Ethyl Benzoate:** An ester, less polar than the acid, will elute second. 3. **Benzoic Acid:** Being the most polar due to the carboxylic acid group, it will elute last.
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