OW Help Oli achieve.macmillanlearning.com © Macmillan Learning X Chapter 12 HW - General, Organic, and Biological Chemistry for Health Scienc 0 Resources Hint Su The succinyl CoA to citrate pathway of the citric acid cycle is shown. Identify the missing intermediates by placing the molecules to the appropriate position. Succinyl CoA CO₂ CH2 GOP-P, GTP CH₂ о COA-SH S-COA A CO2 CH2 C=O HO-C-H CH₂ CH2 CH2 CO₂ CO2 CO₂ Identify the missing cofactors. DEC 5 M N MacBook Pro Citrate H₂O C AcCoA H₂C-CO₂ HỌC CÓ H₂C-CO₂ CoA-SH Answer Bank P H. I C CO₂ HC OH CH₂ H CO₂ CO₂ A Σ (W) Zoom

Step 7 of the citric acid cycle is shown. Which statement best describes what occurs in this step? CO₂ 1 CH || CH + H₂O CO₂ fumarate CO₂™ fumarase HO C-H CH₂ CO₂ malate A) Fumarate undergoes hydrogenation with hydrogens and electrons provided by the enzyme fumarase. B) Fumarate undergoes hydration with the aid of the enzyme fumarase. C) Fumarate undergoes hydrolysis with the aid of the enzyme fumarase. D) Fumarate undergoes reduction with the aid of the cofactor fumarase.

Oxaloacetate  + ADP + Pi + H+      --->     Pyruvate + ATP + HCO3-                               ΔGo’ =  13.91  kJ/mol                     Lactate + NAD+              --->       Pyruvate + NADH + H+                                     ΔGo’ =  25.12 kJ/mol                             Oxaloacetate + GTP       --->            Phosphoenolpyruvate  + GDP + CO2           ΔGo’ = -28.40 kJ/mol                           HCO3- + H+         --->         CO2 + H2O                                                       ΔGo’ =  -41.45  kJ/mol                              GDP + ATP       --->         GTP + ADP                                                          ΔGo’ = -0.003  kJ/mol _________________________________________________________________________________________________________________ Lactate + NAD+ + 2ATP + H2O    --->        Phosphoenolpyruvate + NADH + 2ADP + Pi + 3H+                     From the above information, calculate theΔGo’ for the overall reaction shown…

Oxaloacetate  + ADP + Pi + H+      --->     Pyruvate + ATP + HCO3-                               ΔGo’ =  13.91  kJ/mol                     Lactate + NAD+              --->       Pyruvate + NADH + H+                                     ΔGo’ =  25.12 kJ/mol                             Oxaloacetate + GTP       --->            Phosphoenolpyruvate  + GDP + CO2           ΔGo’ = -28.40 kJ/mol                           HCO3- + H+         --->         CO2 + H2O                                                       ΔGo’ =  -41.45  kJ/mol                              GDP + ATP       --->         GTP + ADP                                                          ΔGo’ = -0.003  kJ/mol _________________________________________________________________________________________________________________ Lactate + NAD+ + 2ATP + H2O    --->        Phosphoenolpyruvate + NADH + 2ADP + Pi + 3H+                     From the above information, calculate the Keq’ for the overall reaction shown…