Nucleus Cytoplasm Neuron -PrpSc -PrpC A prion protein in the PrpSc conformation comes in contact with a PrpC protein, converting it into a PrpSc protein. - Original PrpSc molecule -PrpSc converted from PrpC The 2 PrpSc proteins bind to 2 PrpC proteins, and convert them to PrpSc Over time, all of the PrpC proteins will be converted to PrpSc proteins. FIGURE 25.9 A proposed molecular mechanism of prion diseases. The PrPSc protein catalyzes the conver- sion of a PrP protein to PrP8*. Over time, the PIPS conformation accumulates to high levels, leading to ONLINE ANIMATION symptoms of the prion disease.

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Q: The RNA complement of a protein coding gene is what? A) mRNA B) rRNA C) snRNA D) tRNA

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A:

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Genome annotation

The technique of linking biological information to genome sequences is termed genome annotation. Gene annotation is the method of identifying gene locations and coding sections. It helps us understand what these genes are doing in the body through establishing structural characteristics and linking them to the actions of various proteins.