NH2 HO Atenolol Tenormin® Below is a two-step reaction sequence. What are the steps in the synthesis? `NH2 -NH2 `NH2 base OH Он O The phenolate reacts with the epoxide preferentially over the alkyl halide at the less sterically hindered position. Then, the sterically hindered amine attacks the alkyl chloride. The phenolate reacts with the epoxide preferentially over the alkyl halide at the more sterically hindered position. Then, the sterically hindered amine attacks the alkyl chloride.

NH2 HO Atenolol Tenormin® Below is a two-step reaction sequence. What are the steps in the synthesis? `NH2 -NH2 `NH2 base OH Он O The phenolate reacts with the epoxide preferentially over the alkyl halide at the less sterically hindered position. Then, the sterically hindered amine attacks the alkyl chloride. The phenolate reacts with the epoxide preferentially over the alkyl halide at the more sterically hindered position. Then, the sterically hindered amine attacks the alkyl chloride.

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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