Name the stages of sliding filaments in order. Briefly explain each.

State some major differences between actin filaments and myosin filaments.

1. Draw and label the steps of the sliding filament mechanism in skeletal muscle. This should be four parts (Cross- bridge, power stroke, disassociation, reactivation). On each part, be sure to include the following structures: actin, myosin, troponin, tropomyosin. Also include ATP, myosin ATPase, ADP, Pi, and H* (where important). • Cross-bridge: . Powerstroke: ● Disassociation: ● Reactivation:

What is a significance of the sliding filament mechanism? What is a function of contractile proteins of skeletal muscle sarcomere?

Define the sliding filament model of muscle contraction. Describe the steps of this process.

Explain how microscopic and macroscopic anchoring of musclefilaments enables you to bend your elbow

Explain the concept of the following in regard to muscle cells: sliding filament movement does not need to be a super indepth answer

Name the characteristics of muscles. Name the muscle functions. Name the types of muscles and mention to characteristics of each. Name the organization of muscle tissue from largest to the smallest. Name the major parts of a muscle fiber. Name the three layers of connective tissue membranes in muscles and mention to their locations. Define the structure of a sarcomere. Explain the sliding filament mechanism. Name the stages of sliding filaments in order. Briefly explain each. Explain the structure of NMJ and name the steps of muscle stimulation in order. Name the sources of muscle energy and briefly explain each. Define a motor unit. Name the stages of a muscle twitch in order. Define wave summation, unfused and fused tetanus. Name the types of muscle contraction and briefly explain each. Chapter 12 You should be able to: Classify the nervous system in to two major parts. Name the organs in CNS and PNS. Name the two major types of nerves and mention to their numbers. Mention to…

Can you match the sacromere anatomy with the proper answer from the list below the table graph? Sarcomere Anatomy Description/Reaction Thin Filaments ? Thick Filaments  ? A Band  ? I Band ? M Line ? H Zone ? Z Disc ? A) G-Actin, F-Actin, Troponin, Tropomyosin B) Myosin C) Bisected by the M Line, this area shows only the thick filaments without any thin filamentous overlap D) The point of origin for myosin filaments found in the center of the sarcomere E) An area in the center of the sarcomere marked by the entire length of the thick filaments F) A space between sarcomeres with the z-disc in the center; this region shows Actin's anchorage points and extension without myosin overlap G) Anchoring point for the thin filaments

If you were to watch muscle tissue contract: Under a light microscope, would you see the muscle fibers get narrower, or the striations get thinner? Explain. At the EM level, focusing on one sarcomere, you would be able to see a region of thick filaments overlapping two regions of thin filaments. Use the structure of the thick filaments to explain how ONE region of thick filaments is able to pull in microfilament in two opposite directions (both toward the center of the sarcomere).