Mycophenolate mofetil was administered for 1 month after the intravenous injection of donor cells. The patient was hospitalized on day 21 because of fever with neutropenia and was discharged on day 23 Blood cultures were negative, but the fever rapidly resolved after antibiotics were administered. The patient had no further hospitalizations. Two kidney-biopsy specimens were obtained according to an outpatient protocol at 3 and 12 months. Cyclosporine was gradually tapered and was discontinued 6 months after the transplantation. During those 6 months, there were neither rejection episodes nor clinical manifestations of acute or chronic graft-versus-host disease, and the chimerism was persistent. The patient returned to work about 3 months after the transplantation, and graft biopsy specimens showed normal kidney tissue, no cellular infiltrates were seen. The patient remains in good health 34 months after transplantation. Why would the patient show neutropenia?

Mycophenolate mofetil was administered for 1 month after the intravenous injection of donor cells. The patient was hospitalized on day 21 because of fever with neutropenia and was discharged on day 23 Blood cultures were negative, but the fever rapidly resolved after antibiotics were administered. The patient had no further hospitalizations. Two kidney-biopsy specimens were obtained according to an outpatient protocol at 3 and 12 months. Cyclosporine was gradually tapered and was discontinued 6 months after the transplantation. During those 6 months, there were neither rejection episodes nor clinical manifestations of acute or chronic graft-versus-host disease, and the chimerism was persistent. The patient returned to work about 3 months after the transplantation, and graft biopsy specimens showed normal kidney tissue, no cellular infiltrates were seen. The patient remains in good health 34 months after transplantation. Why would the patient show neutropenia?

Microbiology for Surgical Technologists (MindTap Course List)

2nd Edition

ISBN:9781111306663

Author:Margaret Rodriguez, Paul Price

Publisher:Margaret Rodriguez, Paul Price

Chapter6: Microbial Viability And Growth

Section: Chapter Questions

Problem 4UTM

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