Multistep synthesis of Lidocaine Lab 1) How many grams of starting material do you need? It is given in moles below but how many grams? 2) How to calculate theoretical yield? Part One Method A. Preparation of alpha-Chloro-2,6-dimethylacetanilideCombine 0.033 mol of 2,6-dimethylaniline with 25 mL of glacial acetic acid (or ethyl acetateor THF) and 0.033 mol of alpha-chloroacetyl chloride, in that order, in an appropriately sized Erlenmeyer flask. With the aid of a hot water bath, warm the solution to 40-50°C, remove the flask from the bath, and add a solution of 5 g of sodium acetate trihydrate dissolved in 100 mL of water.

You are in the quest to extract a drug from a known plant with medicinal properties. The structure of the compound is shown below:   Which of the following solvents would be the best choice for extraction? Given solvents:   Select one: A.) A B.) B C.) C D.) D E.) E F.) F

can you answer activity 5?

Which of the following synthetic routes is used in industry to provide epichlorohydrin? Ca(OH)₂ C₂ H₂O a.1 b.2 c3 d.4 Cl₂ 500°C C₂ H₂O Ca(CH) Ch 500 ℃ Ca(OH)₂ Cl₂ 500 °C C₂ H₂O Cl₂ 500 °C Cl₂ H₂O Ca(OH)₂

I need hep writing these chemical equations

Draw and label the following structure below 1. Tartaric acid + NaOH + KMnO4 2. citric acid + NaOH + KMnO4 3.Hydroxamic test for esters 4. hydrolysis reaction for acetic anhydride 5. hydrolysis reaction for acetamide

LAB 12: SYNTHESIS OF LIDOCAINE Experimental Procedure Step 2: Preparation of Lidocaine, 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide – Step 1- Preparation of N-(2,6-Dimethylphenyl)chloroacetamide 1. To a pre-weighed 50-ml round bottomed flask, add the pressed-dry amide 1 and re-weigh the flask to get an exact amount of amide 1. 1. measure out 3.0 mL of 2,6- dimethylaniline into a 10-mL graduated cylinder and set aside in your hood. 2. sequentially add 7.5 mL diethylamine, 25 mL toluene and a few boiling stones. Attach a water-cooled reflux condenser to the round bottomed flask. 2. measure out 15-ml of glacial acetic acid and add it to a 125 mL Erlenmeyer flask. 3. Reflux the reaction mixture for 60 min. 3. Add the amine (2,6- dimethylaniline), via a Pasteur pipet, to the acetic acid in the Erlenmeyer flask. 4. Cool to room temperature, Transfer to a separatory funnel and wash the organic layer with 3x50 mL portions of 4. Transfer 2 mL of 2-chloroacetyl chloride to the Erlenmeyer…

а. ОН 1. TBSCI imidazole, CH2Cl2 A DMF, -18 °C to rt 2. NalO4, CH2Cl2 80% НО OH large excess

An unkown solvent has a formula of C4H8O and molecular weight of 72.11 g/mol. Determine the ff: a.) index of hydrohgen deficiency b.) all possible functional group present base on IHD

Sodium borohydride (NABH4) is a very selective reagent. Which functional groups can sodium borohydride reduce? Choose all that apply. O 1. Aldehyde II. Ester III. Carboxylic Acid O IV. Ketone