Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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List the ions that contribute to electrical signaling in neurons and what side of the neuron their concentration is highest
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- Based upon the changes in permeability seen in the trace below and your knowledge of ion distributions across a cell, predict how ion movements would change during an action potential. Drag and drop each phrase into the appropriate box on the action potential trace. Drag the appropriate labels to their respective targets. Note: not all labels will be used. ►View Available Hint(s) Sodium (Na+) ions move to the axon Sodium (Na) ions move out of the axon Less potassium (K) ions move out of the axon Potassium (K) ions move out of the axon Potassium (K¹) ions move into the axon Sodium (Na) ions stop moving in Membrane potential (mv) +30 +10 0 -10- -30 -50 -70 -90 A PNa 0 PNa 5 6 1 PK Threshold PK 2 Reset Helparrow_forwardIntracellular signaling pathways provide multiple opportunities for the amplification of a response to an extracellular signal. Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. a True Falsearrow_forwardUp-regulation of the reception in the cell signaling means:arrow_forward
- How to fill out each section of the table.arrow_forward13) Draw a graph representing the changes in membrane potential across the axonal membrane before, during, and after an action potential. On your graph, use a highlighter to clearly indicate for which portions of your graph the letter corresponding to each cellular event listed below belongs. List of cellular events: A) All K* channels open B) All Na* channels close C) The Na*/K* ATPase cotransporter transports Na* and K* across the membrane. D) All Na* channels open E) The threshold value of membrane potential is attained. F) All K* channels close G) Some Na* channels open Your graph:arrow_forwardA membrane potential (Vm) labeled axis on the graph In the graph draw the phases of the action potential Include the channels involved and when they open and close matching them to the Vm Indicate the periods in which the action potential can or cannot occurarrow_forward
- A hormone epinephrine binds to G-protein coupled receptor and activate multiple signaling pathways to induce "fight- or-flight" response. In these signaling pathways, which enzyme is responsible for the generation of IP3, a second messenger for calcium release from endoplasmic reticulum? O adenylyl cyclase O protein kinase C O protein kinase A O phospholipase C O calmodulinarrow_forwardThe traces below show the action potential waveforms in an external meidum of different concentrations of * 40 100% 50% 33% 40 1 2 time (msec) calcium chloride potassium O sodiumarrow_forwardPlace the following events in chronological order from 1-8: Nat enters the cell, and depolarization occurs to approximately +30 mV. The voltage across the cell membrane is -70 mV, the resting membrane potential. Upon reaching the peak of the action potential, the VG Nat channels are inactivated by the closing of their inactivation gate and the activation gate of each VG K channel opens. VG K channels close by the closing of their activation gate, and the resting membrane potential is gradually restored. An excitatory post-synaptic potential depolarizes the membrane to threshold and the activation gate of VG Nat channels open. Upon returning to the resting membrane potential, VG Na channels are reset by opening of the inactivation gate and the closing of the activation gate. VG K+ channels are slow to close, resulting in an excess of K* efflux and hyperpolarization. Depolarization occurs as K+ flows out of the cell.arrow_forward
- Choose all that apply [Na*] + [K'] | + + + + This diagram is a drawing of normal conditions that occur in a neuron's axon (not all details are included). This stage that a living neuron would be in, would show that no positive ions are inside the cell current is traveling down the axon the cell will be at rest once the Na ions enter the cell the cell is at rest Na ions are predominantly outside the celarrow_forwardEndocrine Ligand acting on intracellular receptor should be: O Hydrophilic O Hydrophobic O Amphipathic O Macromolecule What kinds of molecules may pass througharrow_forwardDefine the term Neuronal Signaling?arrow_forward
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