Latent Cranial nerve viral DNA Virus moves up cranial nerve. Brainstem The initial infection in children causes cold sores and sometimes sore throat. The virus then moves along a sensory cranial nerve to nerve ganglia near the brain, where it becomes latent. (a) Virus becomes latent after initial infection Reactivation of virus in neuron Virions move down cranial nerve. The latent virus is reactivated, moves back along the sensory nerve to the face and causes cold sores again. (b) Activation of latent virus FIGURE 13.17 Infection Cycle of Herpes Simplex Virus, HSV-1

Biology: The Unity and Diversity of Life (MindTap Course List)
15th Edition
ISBN:9781337408332
Author:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Publisher:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Chapter37: Immunity
Section: Chapter Questions
Problem 2DAA
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What is a provirus?

Latent
Cranial nerve
viral DNA
Virus moves up
cranial nerve.
Brainstem
The initial infection in children causes
cold sores and sometimes sore throat.
The virus then moves along a sensory
cranial nerve to nerve ganglia near the
brain, where it becomes latent.
(a) Virus becomes latent after initial infection
Reactivation of
virus in neuron
Virions move down
cranial nerve.
The latent virus is reactivated, moves
back along the sensory nerve to the
face and causes cold sores again.
(b) Activation of latent virus
FIGURE 13.17 Infection Cycle of Herpes Simplex Virus, HSV-1
Transcribed Image Text:Latent Cranial nerve viral DNA Virus moves up cranial nerve. Brainstem The initial infection in children causes cold sores and sometimes sore throat. The virus then moves along a sensory cranial nerve to nerve ganglia near the brain, where it becomes latent. (a) Virus becomes latent after initial infection Reactivation of virus in neuron Virions move down cranial nerve. The latent virus is reactivated, moves back along the sensory nerve to the face and causes cold sores again. (b) Activation of latent virus FIGURE 13.17 Infection Cycle of Herpes Simplex Virus, HSV-1
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