Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Label the location (number) where the following drugs would act on neurotransmitter systems:
Black widow spider venom______
Botulism toxin ______
Curare ______
Atropine _______
A-MPT ________
Reserpine ______
Fuseric Acid _______
PCPA _____
Propranolol ________
Agomelatine _______
Transcribed Image Text:### Neurotransmitter Lifecycle in Synaptic Transmission
This diagram illustrates the key stages in the lifecycle of neurotransmitters involved in synaptic transmission across a neuron.
1. **Synthesis**:
- Begins with precursor chemicals being converted into neurotransmitters inside the neuron.
2. **Storage**:
- Once synthesized, the neurotransmitters are stored in small vesicles within the neuron.
3. **Release**:
- When an action potential reaches the synaptic terminal, it triggers the release of neurotransmitters into the synaptic cleft.
4. **Receptor Interaction**:
- Released neurotransmitters cross the synaptic cleft and bind to specific receptors on the postsynaptic neuron, initiating a response.
5. **Inactivation**:
- To terminate the signal, neurotransmitters are either broken down or altered to stop their action.
6. **Reuptake**:
- Neurotransmitters that do not bind to receptors are taken back into the presynaptic neuron for reuse or further processing.
7. **Degradation**:
- Excess neurotransmitters in the synaptic cleft are degraded by enzymes.
This process is crucial for effective communication between neurons and is essential for numerous bodily functions and behaviors.
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